It has been suggested that Nucleophilic acyl substitution be merged into this article. (Discuss) Proposed since January 2024.
Chemical reaction which adds an acyl group (R–C=O) to a compound
In chemistry, acylation is a broad class of chemical reactions in which an acyl group (R−C=O) is added to a substrate. The compound providing the acyl group is called the acylating agent. The substrate to be acylated and the product include the following:
alcohols, esters
amines, amides
arenes or alkenes, ketones
A particularly common type of acylation is acetylation, the addition of the acetyl group. Closely related to acylation is formylation, which employ sources of "HCO+ in place of "RCO+".
In chemistry, acylation is a broad class of chemical reactions in which an acyl group (R−C=O) is added to a substrate. The compound providing the acyl...
The Kostanecki acylation is a method used in organic synthesis to form chromones or coumarins by acylation of O-hydroxyaryl ketones with aliphatic acid...
electrophiles, which results in the formation of 1,3-diketones (Stork acylation). It is also effective for activated sp3 alkyl electrophiles, including...
quickly to prevent isomerisation. HATU is commonly encountered in amine acylation reactions (i.e., amide formation). Such reactions are typically performed...
based synthesis, the preferred route to wholly aromatic polyesters. In acylation, the acid begins as an acyl chloride, and thus the polycondensation proceeds...
is present in C3adesArg form. C3adesArg is more commonly named ASP or acylation-stimulating-protein due to its marked stimulating action on triacylglycerol...
In chemistry, amines (/əˈmiːn, ˈæmiːn/, UK also /ˈeɪmiːn/) are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines...
aromatic sulfonation and acylation and alkylating Friedel-Crafts reactions. It further consists of alkylation and acylation. In electrophilic substitution...
ketones, such as those formed in a Friedel-Crafts acylation. The two-step sequence of Friedel-Crafts acylation followed by Clemmensen reduction constitutes...
AlCl3 is a common Lewis-acid catalyst for Friedel-Crafts reactions, both acylations and alkylations. Important products are detergents and ethylbenzene. These...
with Mander's reagent will selectively afford the C-acylation product. Thus, for enolate acylation reactions in which C- vs. O-selectivity is a concern...
resolution acylation of amines. With 10 mol% (-)-PPY* in chloroform at –50 °C, good to very good selectivities were observed in the acylation of amines...
Aniline (from Portuguese anil 'indigo shrub', and -ine indicating a derived substance) is an organic compound with the formula C6H5NH2. Consisting of a...
3-position.[citation needed] Acylation generally occurs at the 2-position, through the use of various methods. Acylation with acid anhydrides and acid...
1139/G10-063. PMID 20962881. Magee T, Seabra MC (April 2005). "Fatty acylation and prenylation of proteins: what's hot in fat". Current Opinion in Cell...
Candida antarctica lipase can be used to catalyze the regioselective acylation of flavonoids. Phytochemical List of antioxidants in food List of phytochemicals...
the radical source used, one side-reaction is acylation, with the ratio between alkylation and acylation depending on the substrate and the reaction conditions...
Similarly, the Friedel-Crafts acylation is a related example of electrophilic aromatic substitution. The reaction involves the acylation of benzene (or many other...
alkylation). Analogously, this reaction can be used as an effective means of acylation. A variety of alkylating and acylating agents including benzylic, allylic...
demonstrated catalytic properties in alkylation, isomerization, oligomerization, acylation, ketalization, esterification, hydrolysis of sugars and ethers, and oxidation...
oxygens, preventing further nucleophilic additions. In the Friedel–Crafts acylation, acid halides act as electrophiles for electrophilic aromatic substitution...
resistance and lipid A acylation protein PagP is a family of several bacterial antimicrobial peptide resistance and lipid A acylation (PagP) proteins. The...
the ring. Many groups can be attached to the ring, via halogenation, acylation, sulfonation, and related processes. Phenol is so strongly activated that...
alternative industrial synthesis developed at Celanese involves firstly direct acylation of phenol with acetic anhydride in the presence of hydrogen fluoride to...
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