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Vitamin D analogues information


The active natural hormonal form of vitamin D is 1,25-dihydroxyvitamin D (1,25(OH)2D). This molecule and other naturally occurring forms of vitamin D, including its precursors and metabolites, have been modified to synthesize pharmaceuticals with potentially greater, or selective, therapeutic actions.[1][2][3][4]

  1. ^ Ashcroft DM, Po AL, Williams HC, Griffiths CE (April 2000). "Systematic review of comparative efficacy and tolerability of calcipotriol in treating chronic plaque psoriasis". BMJ (Clinical Research Ed.). 320 (7240): 963–7. doi:10.1136/bmj.320.7240.963. PMC 27334. PMID 10753146.
  2. ^ Martin KJ, González EA (November 2001). "Vitamin D analogues for the management of secondary hyperparathyroidism". American Journal of Kidney Diseases. 38 (5 Suppl 5): S34–40. doi:10.1053/ajkd.2001.28109. PMID 11689385.
  3. ^ O'Neill JL, Feldman SR (May 2010). "Vitamine D analogue-based therapies for psoriasis". Drugs of Today. 46 (5): 351–60. doi:10.1358/dot.2010.46.5.1473264. PMID 20517536.
  4. ^ Birlea SA, Costin GE, Norris DA (April 2008). "Cellular and molecular mechanisms involved in the action of vitamin D analogs targeting vitiligo depigmentation". Current Drug Targets. 9 (4): 345–59. doi:10.2174/138945008783954970. PMID 18393827.

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Vitamin D analogues

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Doxercalciferol Falecalcitriol Paricalcitol Tacalcitol These modified vitamin D analogues have side chain or other modifications. They aim to reduce the classical...

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Vitamin D

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Many vitamin D analogues have been synthesized. The active vitamin D metabolite calcitriol mediates its biological effects by binding to the vitamin D receptor...

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Psoriasis

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treatment to use.) Vitamin D analogues may be useful with steroids; steroids alone have a higher rate of side effects. Vitamin D analogues may allow less...

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Vitamin D5

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Vitamin D5 (sitocalciferol) is a form of vitamin D. Analogs of calcitriol, a form of vitamin D3, have been proposed for use as antitumor agents. Studies...

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Vitamin B12

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Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. It is one of eight B vitamins. It is required by animals, which...

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Cholecalciferol

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Cholecalciferol, also known as vitamin D3 and colecalciferol, is a type of vitamin D that is made by the skin when exposed to sunlight; it is found in...

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Sclerodactyly

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physical therapy, phototherapy, surgery, topical corticosteroids or vitamin D analogues, and systemic immunosuppressive drugs when the condition is part...

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Parathyroid gland

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associated with decreased calcium, and is generally treated with Vitamin D analogues. The parathyroid glands were first discovered in the Indian rhinoceros...

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Vitamin D receptor

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The vitamin D receptor (VDR also known as the calcitriol receptor) is a member of the nuclear receptor family of transcription factors. Calcitriol (the...

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Medication

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antiseptics, scabicides, pediculicides, tar products, vitamin A derivatives, vitamin D analogues, keratolytics, abrasives, systemic antibiotics, topical...

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Dishman Carbogen Amcis

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The Netherlands: CARBOGEN AMCIS B.V manufactures of Vitamin D2, Vitamin D3, Vitamin D analogues, cholesterol and lanolin related products. The site was...

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Alendronic acid

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eating dairy products or taking the supplement or drug. Highly active vitamin D analogues or fluorides:[clarification needed] no data is available. Concomitant...

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Osteoporosis

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PMID 20068257. Avenell A, Mak JC, O'Connell D (April 2014). "Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older...

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Vitamin K2

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Vitamin K2 or menaquinone (MK) (/ˌmɛnəˈkwɪnoʊn/) is one of three types of vitamin K, the other two being vitamin K1 (phylloquinone) and K3 (menadione)...

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Calcitriol

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vitamin D, normally made in the kidney. It is also known as 1,25-dihydroxycholecalciferol. It is a hormone which binds to and activates the vitamin D...

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Ergocalciferol

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Ergocalciferol, also known as vitamin D2 and nonspecifically calciferol, is a type of vitamin D found in food and used as a dietary supplement. As a supplement...

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Bone fracture

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Alison; Mak, Jenson C. S.; O'Connell, Dianne (14 April 2014). "Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older...

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Betamethasone dipropionate

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calcipotriol) is a combination of corticosteroid (betamethasone) and a vitamin D analogue (calcipotriene) and is used to treat frequent and persistent dermatatoses...

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Topical cream formulation

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Kaposi's sarcoma (alitretinoin) Cutaneous T-cell lymphoma (bexarotene) Vitamin D Analogues Calcipotriene Psoriasis Antimicrobial Agents Azelaic acid, Erythromycin...

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Retinal

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Retinal itself is considered to be a form of vitamin A when eaten by an animal. There are many forms of vitamin A, all of which are converted to retinal,...

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Alfacalcidol

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Alfacalcidol (or 1-hydroxycholecalciferol) is an analogue of vitamin D used for supplementation in humans and as a poultry feed additive. Alfacalcidol...

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Doxercalciferol

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analog of ergocalciferol (vitamin D2). It suppresses parathyroid synthesis and secretion. Docercalciferol is the vitamin D2 analogue of alfacalcidol. It undergoes...

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Thiamine

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Thiamine, also known as thiamin and vitamin B1, is a vitamin, an essential micronutrient for humans and animals. It is found in food and commercially synthesized...

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Wang Yanyi

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PMID 18849498. "Chronic Kidney Disease Medication: Calcium Salts, Vitamin D Analogues, PO4 Scavengers, Hematopoietic Growth Factors, Iron Products, Calcimimetics"...

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Vegan nutrition

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acid, vitamin C, vitamin E, and phytochemicals; and lower in calories, saturated fat, iron, cholesterol, long-chain omega-3 fatty acids, vitamin D, calcium...

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Erythorbic acid

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(isoascorbic acid, D-araboascorbic acid) is a stereoisomer of ascorbic acid (vitamin C). It is synthesized by a reaction between methyl 2-keto-D-gluconate and...

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Parathyroid hormone

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hydroxylation of 25-hydroxy vitamin D, converting vitamin D to its active form (1,25-dihydroxy vitamin D). This activated form of vitamin D increases the absorption...

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Hypercalcaemia

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sarcoidosis, tuberculosis, Paget disease, multiple endocrine neoplasia (MEN), vitamin D toxicity, familial hypocalciuric hypercalcaemia and certain medications...

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