Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Doxercalciferol (or 1-hydroxyergocalciferol, trade name Hectorol) is drug for secondary hyperparathyroidism and metabolic bone disease.[1] It is a synthetic analog of ergocalciferol (vitamin D2). It suppresses parathyroid synthesis and secretion.[2]
Docercalciferol is the vitamin D2 analogue of alfacalcidol.[3] It undergoes 25-hydroxylation in the liver to become the active ercalcitriol, without the involvement of kidneys.[4]
^Sprague S M; Ho L T (2002). "Oral doxercalciferol therapy for secondary hyperparathyroidism in a peritoneal dialysis patient". Clinical Nephrology. 58 (2): 155–160. doi:10.5414/cnp58155. PMID 12227689.
^"Doxercalciferol". Drugs.com.
^Upton, R. A.; Knutson, J. C.; Bishop, C. W.; LeVan, L. W. (1 April 2003). "Pharmacokinetics of doxercalciferol, a new vitamin D analogue that lowers parathyroid hormone". Nephrology Dialysis Transplantation. 18 (4): 750–758. doi:10.1093/ndt/gfg030. PMID 12637645.
^"HECTOROL INJECTION (doxercalciferol)" (PDF). FDA accessdata. Retrieved 21 April 2018.
Doxercalciferol (or 1-hydroxyergocalciferol, trade name Hectorol) is drug for secondary hyperparathyroidism and metabolic bone disease. It is a synthetic...
actions. These include: Alfacalcidol Calcipotriol (calcipotriene) Doxercalciferol Falecalcitriol Paricalcitol Tacalcitol These modified vitamin D analogues...
supplements containing an active form of vitamin D, such as calcitriol, doxercalciferol, paricalcitol; and phosphate binders, which are either calcium-based...
(Metformin), for type 2 diabetes mellitus, marketed by EMD Serono. Hectorol (Doxercalciferol), for parathyroid hormone. Insuman (Human insulin), for type 1 and...
of vitamin D (calcitriol, alfacalcidol, paricalcitol, maxacalcitol, doxercalciferol, among others) cinacalcet renal transplantation haemodialysis five...