Ergocalciferol, also known as vitamin D2 and nonspecifically calciferol, is a type of vitamin D found in food and used as a dietary supplement.[3] As a supplement it is used to prevent and treat vitamin D deficiency.[4] This includes vitamin D deficiency due to poor absorption by the intestines or liver disease.[5] It may also be used for low blood calcium due to hypoparathyroidism.[5] It is used by mouth or injection into a muscle.[4][5]
Excessive doses can result in increased urine production, high blood pressure, kidney stones, kidney failure, weakness, and constipation.[6] If high doses are taken for a long period of time, tissue calcification may occur.[5] Normal doses are safe in pregnancy.[7] It works by increasing the amount of calcium absorbed by the intestines and kidneys.[6] Food in which it is found include some mushrooms.[8]
Ergocalciferol was first described in 1936.[9] Ergocalciferol is available as a generic medication and over the counter.[6] In 2021, it was the 35th most commonly prescribed medication in the United States, with more than 17million prescriptions.[10][11] Certain foods such as breakfast cereal and margarine have ergocalciferol added to them in some countries.[12][13] It is on the World Health Organization's List of Essential Medicines.[14]
^"Summary Basis of Decision (SBD) for Rayaldee". Health Canada. 23 October 2014. Archived from the original on 31 May 2022. Retrieved 29 May 2022.
^"Ergocalciferol Injection BP 300,000IU - Summary of Product Characteristics (SmPC)". (emc). 8 July 2020. Archived from the original on 19 January 2021. Retrieved 10 June 2022.
^Coulston AM, Boushey C, Ferruzzi M (2013). Nutrition in the Prevention and Treatment of Disease. Academic Press. p. 818. ISBN 9780123918840. Archived from the original on 30 December 2016.
^ abBritish national formulary : BNF 69 (69 ed.). British Medical Association. 2015. pp. 703–704. ISBN 9780857111562.
^ abcdWorld Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. p. 498. hdl:10665/44053. ISBN 9789241547659.
^ abc"Ergocalciferol". The American Society of Health-System Pharmacists. Archived from the original on 30 December 2016. Retrieved 8 December 2016.
^Hamilton R (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 227. ISBN 9781284057560.
^"Office of Dietary Supplements - Vitamin D". ods.od.nih.gov. 11 February 2016. Archived from the original on 31 December 2016. Retrieved 30 December 2016.
^Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 451. ISBN 9783527607495. Archived from the original on 30 December 2016.
^"The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
^"Ergocalciferol - Drug Usage Statistics". ClinCalc. Archived from the original on 13 April 2020. Retrieved 14 January 2024.
^Feral P, Hall L (2005). Dining with Friends: The Art of North American Vegan Cuisine. Friends of Animals/Nectar Bat Press. p. 160. ISBN 9780976915904.
^Bennett B, Sammartano R (2012). The Complete Idiot's Guide to Vegan Living (Second ed.). Penguin. p. Chapter 15. ISBN 9781615642793. Archived from the original on 30 December 2016.
^World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.
Ergocalciferol, also known as vitamin D2 and nonspecifically calciferol, is a type of vitamin D found in food and used as a dietary supplement. As a supplement...
compounds in this group are vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol). The major natural source of vitamin D is synthesis of cholecalciferol...
bisporus only contains 0.2 micrograms (8 IU) of vitamin D per 100 g, the ergocalciferol (D2) content increases substantially to 11.2 micrograms (446 IU) after...
in obesity, affect circulating calcifediol. Similarly, vitamin D2, ergocalciferol, can also be 25-hydroxylated to form 25-hydroxyergocalciferol, (ercalcidiol...
0.025 μg, or 25 ng. Dietary reference intake values for vitamin D (ergocalciferol, which is D2, or cholecalciferol, which is D3), or both, have been established...
(fumigant only) zinc phosphide (bait only) Cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2) are used as rodenticides. They are toxic to rodents for...
Compared to other vitamin D compounds in clinical use (cholecalciferol, ergocalciferol), calcitriol has a higher risk of inducing hypercalcemia. However, such...
vitamin D2. The form of vitamin D found in UV-irradiated mushrooms is ergocalciferol, or vitamin D2. This is not the same as cholecalciferol, called vitamin...
with sunlight or artificial ultraviolet light sources Vitamin D2, or ergocalciferol is found in fungus (except alfalfa which is a plantae) and created from...
chanterelles produce a rich amount of vitamin D2 (35% DV) – also known as ergocalciferol. Though records of chanterelles being eaten date back to the 16th century...
(cholecalciferol) is typically absorbed more readily than vitamin D2 (ergocalciferol). Osteomalacia due to malabsorption may require treatment by injection...
class of secosteroids (open-ring steroids): Vitamin D forms such as ergocalciferol, cholecalciferol, and calcitriol Steroids can be classified based on...
molecular compounds of ergocalciferol with lumisterol, 1:1 fat 15 μg/15 μg rickets and osteomalacia hypervitaminosis D D2 ergocalciferol fat sunlight-exposed...
also - provitamin A carotenoids)) Vitamin C (Ascorbic acid) Vitamin D Ergocalciferol Cholecalciferol Vitamin E (tocopherols and tocotrienols) Vitamin K Vitamin...
premature aging. Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2), are used in rodenticides due to their ability to induce hypercalcemia...
pure beta-carotene in oil, crystalline ascorbic acid, and crystalline ergocalciferol. This same commission also established early standards for biologics...
a biological precursor of vitamin D2, the chemical name of which is ergocalciferol. Exposure of white button mushrooms to UV-C irradiation at 0.403 mW...
analog of 1,25-dihydroxyergocalciferol, the active form of vitamin D2 (ergocalciferol). It was patented in 1989 and approved for medical use in 1998. Its...
D from sunlight. Since vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol) are fat-soluble, humans and other animals with a skeleton need to store...
hypercalcemia. Plants such as Cestrum diurnum, and Solanum malacoxylon contain ergocalciferol or cholecalciferol which cause the onset of hypercalcemia. Consuming...
the liver that does not require renal hydroxylation like vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). DHT has a rapid onset of action (2...
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