Ability of some viruses to lie dormant within a cell
"Viral reservoir" redirects here. For a population of organisms in which a pathogen naturally lives and reproduces, see Natural reservoir.
Virus latency (or viral latency) is the ability of a pathogenic virus to lie dormant (latent) within a cell, denoted as the lysogenic part of the viral life cycle.[1] A latent viral infection is a type of persistent viral infection which is distinguished from a chronic viral infection. Latency is the phase in certain viruses' life cycles in which, after initial infection, proliferation of virus particles ceases. However, the viral genome is not eradicated. The virus can reactivate and begin producing large amounts of viral progeny (the lytic part of the viral life cycle) without the host becoming reinfected by new outside virus, and stays within the host indefinitely.[2]
Virus latency is not to be confused with clinical latency during the incubation period when a virus is not dormant.
^Villarreal, Luis P. (2005). Viruses and the Evolution of Life. Washington, ASM Press.
^N.J. Dimmock et al. "Introduction to Modern Virology, 6th edition." Blackwell Publishing, 2007.
Viruslatency (or viral latency) is the ability of a pathogenic virus to lie dormant (latent) within a cell, denoted as the lysogenic part of the viral...
to produce the LAT (latency-associated transcripts) that play an important role in establishing HSV latency (herpes simplex virus). VZV virions are spherical...
including cancer. §JC virus & BK virus only cause disease in immunocompromised patients Clinical latencyViruslatency "About HIV/AIDS | HIV Basics | HIV/AIDS"...
HHV Latency Associated Transcript (HHV LAT) is a length of RNA which accumulates in cells hosting long-term, or latent, Human Herpes Virus (HHV) infections...
of the herpes simplex virus, which causes cold sores, to remain in a dormant state within the human body. This is called latency and is a characteristic...
late lytic, are distinct from the latency stage. In the case of HSV-1, no protein products are detected during latency, whereas they are detected during...
reliance on small-animal models), its latency is less well understood than that of the herpes simplex virus. Virus-specific proteins continue to be made...
undergo latency in both of these cells. A remarkable fact concerning the latency of EBV is that different patterns of expression exist while it is latent, known...
disease symptoms. Thus, while herpes viruses can enter both the lytic and lysogenic cycles, latency allows the virus to survive and evade detection by the...
Incubation period (also known as the latent period or latency period) is the time elapsed between exposure to a pathogenic organism, a chemical, or radiation...
contraction of the muscle Viruslatency, a period during which a virus remains dormant in a cell and does not proliferate Latency stage, Sigmund Freud's...
long-term latency is symptom-free.[citation needed] Chromatin dynamics regulate the transcription competency of entire herpes virus genomes. When the virus enters...
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Cohrs RJ (July 2015). "A comparison of herpes simplex virus type 1 and varicella-zoster viruslatency and reactivation". The Journal of General Virology...
latency, and the consequent viral reservoir in CD4+ T cells, dendritic cells, as well as macrophages, is the main barrier to eradication of the virus...
establish latency via stochastic noise, and that T-cell relaxation is not sufficient to drive latency. This model proposes to explain why many latent proviruses...
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