activation of cysteine-type endopeptidase activity involved in apoptotic process
activation of NF-kappaB-inducing kinase activity
immune response
apoptotic process
signal transduction
regulation of signaling receptor activity
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
9966
326623
Ensembl
ENSG00000181634
ENSMUSG00000050395
UniProt
O95150
Q5UBV8
RefSeq (mRNA)
NM_005118 NM_001204344
NM_177371
RefSeq (protein)
NP_001191273 NP_005109
NP_796345
Location (UCSC)
Chr 9: 114.78 – 114.81 Mb
Chr 4: 63.64 – 63.66 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Vascular endothelial growth inhibitor (VEGI), also known as TNF-like ligand 1A (TL1A) and TNF superfamily member 15 (TNFSF15), is protein that in humans is encoded by the TNFSF15 gene. VEGI is an anti-angiogenic protein.[5] It belongs to tumor necrosis factor (ligand) superfamily, where it is member 15.[6] It is the sole known ligand for death receptor 3,[7] and it can also be recognized by decoy receptor 3.
^ abcGRCh38: Ensembl release 89: ENSG00000181634 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000050395 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Hoffmann R, Valencia A (Jul 2004). "A gene network for navigating the literature". Nature Genetics. 36 (7): 664. doi:10.1038/ng0704-664. PMID 15226743.
^"Entrez Gene: TNFSF15 tumor necrosis factor (ligand) superfamily, member 15".
^Wang EC (Sep 2012). "On death receptor 3 and its ligands…". Immunology. 137 (1): 114–116. doi:10.1111/j.1365-2567.2012.03606.x. PMC 3449252. PMID 22612445.
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Global Information
