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Toxicity information


Toxicity
The skull and crossbones is a common symbol for toxicity.

Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism.[1] Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell (cytotoxicity) or an organ such as the liver (hepatotoxicity). Sometimes the word is more or less synonymous with poisoning in everyday usage.

A central concept of toxicology is that the effects of a toxicant are dose-dependent; even water can lead to water intoxication when taken in too high a dose, whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect. Toxicity is species-specific, making cross-species analysis problematic. Newer paradigms and metrics are evolving to bypass animal testing, while maintaining the concept of toxicity endpoints.[2]

  1. ^ "Definition of TOXICITY". 30 July 2023.
  2. ^ "Toxicity Endpoints & Tests". AltTox.org. Archived from the original on October 1, 2018. Retrieved 25 February 2012.

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Toxicity

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Acute toxicity

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described as acute toxicity, the adverse effects should occur within 14 days of the administration of the substance. Acute toxicity is distinguished from...

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Copper toxicity

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copper level in the blood) can lead to copper toxicity if it persists and rises high enough. Chronic toxicity by copper is rare. The suggested safe level...

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Methanol toxicity

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Methanol toxicity (also methanol poisoning) is poisoning from methanol, characteristically via ingestion. Symptoms may include a decreased level of consciousness...

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Toxicity class

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Lithium toxicity

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severe toxicity hemodialysis is recommended. The risk of death is generally low. Acute toxicity generally has better outcomes than chronic toxicity. In the...

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Toxicity label

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on pesticide containers in India identifying the level of toxicity (that is, the toxicity class) of the contained pesticide. The schemes follows from...

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Chronic toxicity

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Chronic toxicity can be directly lethal but are more commonly sublethal, including changes in growth, reproduction, or behavior. Chronic toxicity is in...

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Metal toxicity

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Metal toxicity or metal poisoning is the toxic effect of certain metals in certain forms and doses on life. Some metals are toxic when they form poisonous...

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Toxication

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Toxication, toxification or toxicity exaltation is the conversion of a chemical compound into a more toxic form in living organisms or in substrates such...

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Digoxin toxicity

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1785 by William Withering. Digoxin toxicity is often divided into acute or chronic toxicity. In both of these toxicity, cardiac effects are of the greatest...

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The Toxic Avenger

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Toxic Positivity

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Toluene toxicity

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Toluene toxicity refers to the harmful effects caused by toluene on the body. While a significant amount of toluene, 25%–40%, is exhaled unchanged via...

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Protein toxicity

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Protein toxicity is the effect of the buildup of protein metabolic waste compounds, like urea, uric acid, ammonia, and creatinine. Protein toxicity has many...

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Serotonin syndrome

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features of NMS differ significantly from those of serotonin toxicity. Serotonin toxicity has a rapid onset after the administration of a serotonergic...

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Paracetamol poisoning

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from toxicity occurs 4 to 18 days later. Paracetamol poisoning can occur accidentally or as an attempt to die by suicide. Risk factors for toxicity include...

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Toxicity category rating

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established four Toxicity Categories for acute hazards of pesticide products, with "Category I" being the highest toxicity category (toxicity class). Most...

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Toxic vacuolation

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granulation. The finding is also associated with bacterial infection, alcohol toxicity, liver failure, and treatment with granulocyte colony-stimulating factor...

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Developmental toxicity

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Developmental toxicity is any developmental malformation that is caused by the toxicity of a chemical or pathogen. It is the structural or functional...

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Globally Harmonized System of Classification and Labelling of Chemicals

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Reproductive toxicity includes adverse effects on sexual function and fertility in adult males and females, as well as developmental toxicity in offspring...

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Fluoride toxicity

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Fluoride toxicity is a condition in which there are elevated levels of the fluoride ion in the body. Although fluoride is safe for dental health at low...

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Zinc toxicity

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Zinc toxicity is a medical condition involving an overdose on, or toxic overexposure to, zinc. Such toxicity levels have been seen to occur at ingestion...

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Toxic shock syndrome

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Toxic shock syndrome (TSS) is a condition caused by bacterial toxins. Symptoms may include fever, rash, skin peeling, and low blood pressure. There may...

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Vitamin D toxicity

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Vitamin D toxicity, or hypervitaminosis D is the toxic state of an excess of vitamin D. The normal range for blood concentration in adults is 20 to 50...

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