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Toxic vacuolation information


Toxic vacuolation
Other namesToxic vacuolization
A vacuolated neutrophil
A vacuolated neutrophil
SpecialtyHematology
CausesSepsis, bacterial infection, alcohol toxicity, liver failure, G-CSF treatment

Toxic vacuolation, also known as toxic vacuolization,[1] is the formation of vacuoles in the cytoplasm of neutrophils in response to severe infections or inflammatory conditions.[2][3]

  1. ^ Betty Ciesla (27 November 2018). "Chapter 10: Abnormalities of white blood cells: quantitative, qualitative and the lipid storage diseases". Hematology in Practice. F.A. Davis. p. 153. ISBN 978-0-8036-6825-6.
  2. ^ Mary Louise Turgeon (14 April 2014). "Leukocytes and platelets". Linne & Ringsrud's Clinical Laboratory Science - E-Book: The Basics and Routine Techniques (6th ed.). Elsevier Health Sciences. p. 318. ISBN 978-0-323-29280-1.
  3. ^ Barbara J. Bain (11 November 2014). "Chapter 3: Morphology of blood cells". Blood Cells: A Practical Guide (5 ed.). Wiley. pp. 112–113. ISBN 978-1-118-81729-2.

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information on size, cytoplasm, nucleoli, basophilia (color of cytoplasm), and vacuolation (bubble-like properties). While some clinicians still use the FAB scheme...

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protein complex that causes a progressive vacuolation in the epithelial cells leading to their death. The vacuolation has also been associated with promoting...

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models with this mutation do not exhibit the classical mitochondrial vacuolation pathology seen in G93A and G37R ALS mice and unlike G93A mice, deficiency...

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AB5 toxin

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glycans on cells with high affinity. Just subB is sufficient to cause vacuolation of vero cells. Neu5GC is not made by humans but is acquired from food...

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clasmatodendrosis of astrocytes, defined by cytoplasmic swelling and vacuolation, beading and dissolution of their processes and nuclear alterations resembling...

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pharmacological inhibition causes lysosome enlargement and cytoplasmic vacuolation due to impaired PtdIns(3,5)P2 synthesis and impaired lysosome fission...

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research by John Olney. In 1989, John Olney discovered that neuronal vacuolation and other cytotoxic changes ("lesions") occurred in brains of rats administered...

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symptoms such as swelling of the endoplasmic reticulum, disintegration and vacuolation of the cytoplasm, as well as fibrous material appearing in those vacuolated...

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