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Tissue microarray information


A Tissue MicroArray Block
0.6 mm core Tissue MicroArray Block
A Tissue MicroArray Section

Tissue microarrays (also TMAs) consist of paraffin blocks in which up to 1000[1] separate tissue cores are assembled in array fashion to allow multiplex histological analysis.

  1. ^ "Yale University Core Tissue MicroArray Facility". Archived from the original on 10 May 2009.

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Tissue microarray

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Tissue microarrays (also TMAs) consist of paraffin blocks in which up to 1000 separate tissue cores are assembled in array fashion to allow multiplex...

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Microarray

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interactions Tissue microarrays Cellular microarrays (also called transfection microarrays) Chemical compound microarrays Antibody microarrays Glycan arrays...

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DNA microarray

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A DNA microarray (also commonly known as DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA...

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Immunohistochemistry

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and tissues. The combination of immunohistochemistry and tissue microarrays provides protein expression patterns in a large number of different tissue types...

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Biochip

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Patch Clamp Protein array Sequencing Single nucleotide polymorphism Tissue microarray "High-Level Synthesis of Digital Microfluidic Biochips" (PDF). Duke...

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Adipose tissue

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and has been used extensively in the study of adipose tissue. One such study used microarray analysis in conjunction with Ingenuity IPA software to look...

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Protein microarray

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A protein microarray (or protein chip) is a high-throughput method used to track the interactions and activities of proteins, and to determine their function...

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Antibody microarray

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detected. Antibody microarrays are often used for detecting protein expression from various biofluids including serum, plasma and cell or tissue lysates. Antibody...

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TMA

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theory of Forms Thrombotic microangiopathy Tissue microarray, device for analysing many histological tissue samples Transcription mediated amplification...

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Random forest

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Belldegrun AS, Palotie A, Horvath S (April 2005). "Tumor classification by tissue microarray profiling: random forest clustering applied to renal cell carcinoma"...

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Chromogenic in situ hybridization

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Hybridization Analysis of Formalin Fixed Paraffin Embedded Tissues, Including Tissue Microarrays". Fluorescence in situ Hybridization (FISH). Methods in...

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MALDI imaging

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of N-glycans in formalin-fixed paraffin embedded clinical tissue blocks and tissue microarrays". PLOS ONE. 9 (9): e106255. Bibcode:2014PLoSO...9j6255P....

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Frozen tissue array

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Schoenberg Fejzo M, Slamon DJ. Tissue microarrays from frozen tissues-OCT technique. Methods Mol Biol. 2010, 664:73-80. "Frozen Tissue Array". BioChain Institute...

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Cytotechnology

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assurance. For example, when a cytotechnologist is working to construct a tissue microarray (TMA), they must check in with the supervising pathologist at multiple...

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Chordoma

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were phosphorylated in 92%, 96% and 98% of cases, respectively. In a tissue microarray containing 21 chordomas Platelet-derived growth factor receptor-beta...

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Reverse phase protein lysate microarray

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A reverse phase protein lysate microarray (RPMA) is a protein microarray designed as a dot-blot platform that allows measurement of protein expression...

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Fluorescence in situ hybridization

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gastric mucosa-associated lymphoid tissue lymphomas: a fluorescent in situ hybridization study using a tissue microarray approach". Human Pathology. 39 (4):...

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Tissue inhibitor of metalloproteinase

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Tissue inhibitors of metalloproteinases (TIMPs) are specific endogenous protease inhibitors to the matrix metalloproteinases. There are four TIMPs; TIMP1...

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Bioinformatics

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in a tissue context can be achieved through affinity proteomics displayed as spatial data based on immunohistochemistry and tissue microarrays. Gene...

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In situ hybridization

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Huntsman, David (2007-05-01). "Fluorescent in situ hybridization on tissue microarrays: challenges and solutions". Journal of Molecular Histology. 38 (2):...

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Transcriptomics technologies

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biological sciences. There are two key contemporary techniques in the field: microarrays, which quantify a set of predetermined sequences, and RNA-Seq, which...

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Biomarker discovery

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biomarkers includes: 2D-PAGE LC-MS SELDI-TOF (or MALDI-TOF) Antibody array Tissue microarray The term metabolomic has been recently introduced to address the global...

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Comparative genomic hybridization

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the human genome, with these fragments being used as probes on the DNA microarray. Now probes of various origins such as cDNA, genomic PCR products and...

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Hybridization probe

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methods, and in other gene technologies, such as nucleic acid and tissue microarrays. Scorpion® probes Molecular Beacon probes TaqMan® probes LNA® (Locked...

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Glutamate carboxypeptidase II

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neoplastic tissues and its sensitivity and specificity in prostate adenocarcinoma: an immunohistochemical study using multiple tumour tissue microarray technique"...

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Automated tissue image analysis

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Foran, D. J. (2006). "Analytica Chimica Acta - Advances in cancer tissue microarray technology: Towards improved understanding and diagnostics". Analytica...

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Chemical compound microarray

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This microarray format is very similar to DNA microarray, protein microarray and antibody microarray. In chemical genetics research, they are routinely...

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CABLES1

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cables protein expression in human non-small cell lung cancer: a tissue microarray study". Hum. Pathol. 34 (2): 143–9. doi:10.1053/hupa.2003.26. PMID 12612882...

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Zinc finger protein 684

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of gene expression, ZNF684 has ubiquitous expression in all human tissues. Microarray data illustrates higher expression of ZNF684 within the liver. This...

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