Loose connective tissue composed mostly by adipocytes
"Adipose" redirects here. For the fictional creature from Doctor Who, see List of Doctor Who universe creatures and aliens (0–9, A–G) § Adipose.
See also: Fat
Adipose tissue
Pig belly fat (white)
Adipose tissue is one of the main types of connective tissue.
Pronunciation
/ˈædɪˌpoʊs/ⓘ
Identifiers
MeSH
D000273
FMA
20110
Anatomical terminology
[edit on Wikidata]
Adipose tissue (also known as body fat or simply fat) is a loose connective tissue composed mostly of adipocytes.[1][2] It also contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, vascular endothelial cells and a variety of immune cells such as adipose tissue macrophages. Its main role is to store energy in the form of lipids, although it also cushions and insulates the body.
Previously treated as being hormonally inert, in recent years adipose tissue has been recognized as a major endocrine organ,[3] as it produces hormones such as leptin, estrogen, resistin, and cytokines (especially TNFα).[2] In obesity, adipose tissue is implicated in the chronic release of pro-inflammatory markers known as adipokines, which are responsible for the development of metabolic syndrome—a constellation of diseases including type 2 diabetes, cardiovascular disease and atherosclerosis.[2][4]
Adipose tissue is derived from preadipocytes and its formation appears to be controlled in part by the adipose gene. The two types of adipose tissue are white adipose tissue (WAT), which stores energy, and brown adipose tissue (BAT), which generates body heat. Adipose tissue—more specifically brown adipose tissue—was first identified by the Swiss naturalist Conrad Gessner in 1551.[5]
^Birbrair A, Zhang T, Wang ZM, Messi ML, Enikolopov GN, Mintz A, Delbono O (August 2013). "Role of pericytes in skeletal muscle regeneration and fat accumulation". Stem Cells and Development. 22 (16): 2298–2314. doi:10.1089/scd.2012.0647. PMC 3730538. PMID 23517218.
^ abcYe RZ, Richard G, Gévry N, Tchernof A, Carpentier AC (January 2022). "Fat Cell Size: Measurement Methods, Pathophysiological Origins, and Relationships With Metabolic Dysregulations". Endocrine Reviews. 43 (1): 35–60. doi:10.1210/endrev/bnab018. PMC 8755996. PMID 34100954.
^Kershaw EE, Flier JS (June 2004). "Adipose tissue as an endocrine organ". The Journal of Clinical Endocrinology and Metabolism. 89 (6): 2548–2556. doi:10.1210/jc.2004-0395. PMID 15181022.
^Mancuso P (May 2016). "The role of adipokines in chronic inflammation". ImmunoTargets and Therapy. 5 (2016): 47–56. doi:10.2147/ITT.S73223. PMC 4970637. PMID 27529061.
Adiposetissue (also known as body fat or simply fat) is a loose connective tissue composed mostly of adipocytes. It also contains the stromal vascular...
known as lipocytes and fat cells, are the cells that primarily compose adiposetissue, specialized in storing energy as fat. Adipocytes are derived from mesenchymal...
Bone marrow adiposetissue (BMAT), sometimes referred to as marrow adiposetissue (MAT), is a type of fat deposit in bone marrow. It increases in states...
consists of loose connective tissue (including reticular connective tissue and adiposetissue) and dense connective tissue (subdivided into dense regular...
oxaloacetate to phosphoenolpyruvate. Glyceroneogenesis is observed mainly in adiposetissue, and in the liver. A significant biochemical pathway regulates cytosolic...
the designations areolar tissue, adiposetissue, and reticular tissue have been listed as subsets of loose connective tissue. However, they are no longer...
GLUT4 is the insulin-regulated glucose transporter found primarily in adiposetissues and striated muscle (skeletal and cardiac). The first evidence for...
to be specific, adiposetissue.[citation needed] Two types of adiposetissue exist: white adiposetissue (WAT) and brown adiposetissue (BAT). The formation...
composed of several adipose depots including mesenteric, epididymal white adiposetissue (EWAT), and perirenal fat. An excess of adipose visceral fat is known...
tonsil tissues. ILC2s are essential in the maintenance of homeostasis in lean and healthy adiposetissue. ILC2s resident in visceral adiposetissue produce...
bloodletting, sebum excretion, and hair growth. In animals, adiposetissue, or fatty tissue is the body's means of storing metabolic energy over extended...
(muscle cells) and adipocytes (fat cells which give rise to marrow adiposetissue). Mesenchymal stem cells (MSCs), a term first named (1991) by Arnold...
become overweight or obese, generally defined as having more body fat (adiposetissue) than is considered good for health. The Body Mass Index (BMI) measures...
breast is composed of differing layers of tissue, predominantly two types: adiposetissue; and glandular tissue, which affects the lactation functions of...
The adiposetissue expandability hypothesis posits that metabolic dysregulation that appears to be caused by excess weight, such as type 2 diabetes and...
mostly in cosmetic surgery with the intention of removing unwanted adiposetissue. The procedure may be invasive, as with liposuction, or noninvasive...
protein is a protein hormone predominantly made by adipocytes (cells of adiposetissue). Its primary role is likely to regulate long-term energy balance. As...
brown adiposetissue (brown fat) that is present in almost all eutherians (swine being the only exception currently known). Brown adiposetissue has a...
humans, it is encoded by the ADIPOQ gene and is produced primarily in adiposetissue, but also in muscle and even in the brain. Adiponectin is a 244-amino-acid-long...
lymphoid organs (lymph node stromal cells, red bone marrow, and spleen). Adiposetissue is held together by reticular fibers. They can be identified in histology...
hormonal functions. Storage body fat consists of fat accumulation in adiposetissue, part of which protects internal organs in the chest and abdomen. A...
Blubber is a thick layer of vascularized adiposetissue under the skin of all cetaceans, pinnipeds, penguins, and sirenians. It was present in many marine...
of adiposetissue macrophages has therefore been considered a possible therapeutic target to treat obesity-related diseases. Although adiposetissue macrophages...
around elucidating the function and physiological importance of brown adiposetissue, as well as the importance of thermoneutrality in translating mouse...
peptide, and cortisol. In the body, stores of fat are referred to as adiposetissue. In these areas, intracellular triglycerides are stored in cytoplasmic...
distributed in adipose, heart, and skeletal muscle tissue, as well as in lactating mammary glands. In brief, LPL is secreted from heart, muscle and adipose parenchymal...
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