Tight junction protein ZO-2 is a protein that in humans is encoded by the TJP2 gene.[5]
Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton [supplied by OMIM].[6]
^ abcGRCh38: Ensembl release 89: ENSG00000119139 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000024812 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Duclos F, Rodius F, Wrogemann K, Mandel JL, Koenig M (November 1994). "The Friedreich ataxia region: characterization of two novel genes and reduction of the critical region to 300 kb". Hum Mol Genet. 3 (6): 909–914. doi:10.1093/hmg/3.6.909. PMID 7951235.
^"Entrez Gene: TJP2 tight junction protein 2 (zona occludens 2)".
and 29 Related for: Tight junction protein 2 information
Tightjunctionprotein ZO-2 is a protein that in humans is encoded by the TJP2 gene. Tightjunctionproteins (TJPs) belong to a family of membrane-associated...
Zonula occludens-1 ZO-1, also known as Tightjunctionprotein-1 is a 220-kD peripheral membrane protein that is encoded by the TJP1 gene in humans. It...
proteins composing the tightjunctions. These proteins consist of both transmembrane and cytoplasmic proteins. The three major transmembrane proteins...
plasma-membrane protein localized at the tightjunctions. Together with Claudins, and zonula occludens-1 (ZO-1), occludin has been considered a staple of tight junctions...
adherens junctions (or zonula adherens, intermediate junction, or "belt desmosome") are protein complexes that occur at cell–cell junctions and cell–matrix...
approximately 40 proteins identified to be involved in tightjunctions. These proteins can be classified into four major categories;signalling proteins. Scaffolding...
cholestasis in humans. USP53 localizes at cellular tightjunctions and interacts with tightjunctionprotein2 (TJP2). Mutations in TJP2 have also been shown...
molecule adheres to other tightjunctionproteins like PAR-3 and ZO-1. JAM-2 has been shown to interact with these proteins, primarily through the PDZ1...
1952. They were named in 1969 after the 2-4 nm gap they bridge between cell membranes. Gap junctions use protein complexes known as globules to connect...
Claudin-1 is a protein that in humans is encoded by the CLDN1 gene. It belongs to the group of claudins. Tightjunctions represent one mode of cell-to-cell...
known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. It is a member of the claudin protein family. Tightjunctions represent one mode...
synthetic eight amino acid peptide that functions as a tightjunction regulator and reverses leaky junctions to their normally closed state. It has been studied...
transcription regulator protein 1 (WWTR1), also known as Transcriptional coactivator with PDZ-binding motif (TAZ), is a protein that in humans is encoded...
transport. Claudins, such as CLDN19, are transmembrane proteins found at tightjunctions. Tightjunctions form barriers that control the passage of ions and...
to anchoring junctions, intracellular domains of these tightjunctionproteins are bound with scaffold proteins that keep these proteins in clusters and...
“to form a belt around”) is a cytosolic protein encoded by the CGN gene in humans localized at tightjunctions (TJs) of vertebrate epithelial and endothelial...
Gap junction alpha-1 protein (GJA1), also known as connexin 43 (Cx43), is a protein that in humans is encoded by the GJA1 gene on chromosome 6. As a connexin...
Zonulin (haptoglobin 2 precursor) is a protein that increases the permeability of tightjunctions between cells of the wall of the digestive tract. It...
family of proteins which, along with occludin, are the most important components of the tightjunctions (zonulae occludentes). Tightjunctions establish...
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions...
claudin family. Claudins are integral membrane proteins and components of tightjunction strands. Tightjunction strands serve as a physical barrier to prevent...
Tightjunctionprotein ZO-3 is a protein that in humans is encoded by the TJP3 gene. TJP3 has been shown to interact with tightjunctionprotein 1. GRCh38:...
connexin hemichannel, is an assembly of six proteins called connexins that form the pore for a gap junction between the cytoplasm of two adjacent cells...
family of proteins, which form tightjunction strands in epithelial cells . [supplied by OMIM] Isoform 2 (Claudin 18.2) is abundant in gastric tumors...
the formation of tightjunctions between epithelial cells. Tightjunctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically...
Tightjunction-associated protein 1 is a protein that in humans is encoded by the TJAP1 gene. TJAP1 has been shown to interact with DLG1. GRCh38: Ensembl...
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