Thrombin inhibitor information

thrombin inhibitors (DTIs) are a class of medication that act as anticoagulants (delaying blood clotting) by directly inhibiting the enzyme thrombin (factor...

Thrombin inhibitor may refer to: Direct thrombin inhibitor Indirect thrombin inhibitor, such as warfarin This disambiguation page lists articles associated...

enzyme complex to form thrombin. Thrombin (Factor IIa) (EC 3.4.21.5, fibrinogenase, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated...

oral anticoagulants. These agents include direct thrombin inhibitor (dabigatran) and factor Xa inhibitor (rivaroxaban, apixaban, betrixaban and edoxaban)...

Angiomax and Angiox, among others, is a specific and reversible direct thrombin inhibitor (DTI). Chemically, it is a synthetic congener of the naturally occurring...

Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. In 2000, argatroban was licensed by the Food and Drug Administration...

direct thrombin inhibitor, was the first member of this class that can be taken orally. It acts solely by inhibiting the actions of thrombin. It is taken...

it has fewer interactions with other medications. It is a direct thrombin inhibitor. Dabigatran was approved for medical use in the United States in 2010...

The thrombin time (TT), also known as the thrombin clotting time (TCT), is a blood test that measures the time it takes for a clot to form in the plasma...

based on its ability to inhibit the procoagulant activity of thrombin. Hirudin is the most potent natural inhibitor of thrombin. Unlike antithrombin, hirudin...

The product encoded by this gene is a serine protease inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene...

Direct thrombin inhibitors (DTIs) are a class of anticoagulant drugs that can be used to prevent and treat embolisms and blood clots caused by various...

hirudin, or direct thrombin inhibitors, whereas the thrombin time will be prolonged in these samples. Reptilase also differs from thrombin by releasing fibrinopeptide...

by thrombin, FXIa, FXII, and FXa. The activation of FX (to form FXa) by TF-FVIIa is almost immediately inhibited by tissue factor pathway inhibitor (TFPI)...

generally treat to avoid thrombosis. Treatment may include a direct thrombin inhibitor, such as lepirudin or argatroban. Other "blood thinners" sometimes...

Inogatran (INN) is a low molecular weight peptidomimetic thrombin inhibitor. Inogatran was developed for the potential treatment of arterial and venous...

Factor Xa is inactivated by protein Z-dependent protease inhibitor (ZPI), a serine protease inhibitor (serpin). The affinity of this protein for factor Xa...

Protease inhibitor (pharmacology) Protease inhibitor (biology) TopFIND - database of protease specificity, substrates, products and inhibitors MEROPS -...

Combinations B01AC56 Acetylsalicylic acid, combinations with proton pump inhibitors B01AD01 Streptokinase B01AD02 Alteplase B01AD03 Anistreplase B01AD04 Urokinase...

Drug Administration (FDA): dabigatran (thrombin inhibitor), apixaban, rivaroxaban, edoxaban (all factor Xa inhibitors). In the United Kingdom, the NICE guidelines...

refers to the binding of thrombin to fibrin, after thrombin has activated fibrinogen, at a non-catalytic binding site of thrombin. Antithrombin II (AT II)...

These direct factor Xa inhibitors can be administered orally, as can dabigatran etexilate, which is a direct thrombin inhibitor. Fondaparinux, Rivaroxaban...

prostate cancer. Protein C inhibitor is activated by heparin against thrombin. Protein C inhibitor (PCI) is serine protease inhibitor of serpin type that is...