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Thiomuscimol information


Thiomuscimol
Names
Preferred IUPAC name
5-(Aminomethyl)-1,2-thiazol-3-ol
Identifiers
CAS Number
  • 62020-54-6
3D model (JSmol)
  • Interactive image
ChemSpider
  • 5251
PubChem CID
  • 5448
CompTox Dashboard (EPA)
  • DTXSID00211078 Edit this at Wikidata
InChI
  • InChI=1S/C4H6N2OS/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)
    Key: QVBUOPGWPXUAHT-UHFFFAOYSA-N
SMILES
  • C1=C(SN=C1O)CN
Properties
Chemical formula
C4H6N2OS
Molar mass 130.17 g·mol−1
Melting point 140 °C (decomp.)[1]
Acidity (pKa) 6.06 ± 0.03, 8.85 ± 0.04 (H2O, 21 °C)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Thiomuscimol is a GABAA receptor agonist which is structurally related to muscimol.[2]

  1. ^ Lykkeberg, Jytte; Krogsgaard-Larsen, Povl; Garegg, Per J.; Norberg, Thomas; Pilotti, Anne-Marie; Anthonsen, T. (1976). "Structural Analogues of GABA. Synthesis of 5-Aminomethyl-3-isothiazolol (Thiomuscimol)". Acta Chemica Scandinavica. 30b: 781–785. doi:10.3891/acta.chem.scand.30b-0781.
  2. ^ Krogsgaard-Larsen, P; Hjeds, H; Curtis, DR; Lodge, D; Johnston, GA (1979). "Dihydromuscimol, thiomuscimol and related heterocyclic compounds as GABA analogues". Journal of Neurochemistry. 32 (6): 1717–24. doi:10.1111/j.1471-4159.1979.tb02284.x. PMID 448364. S2CID 1393563.

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Thiomuscimol

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Thiomuscimol is a GABAA receptor agonist which is structurally related to muscimol. Lykkeberg, Jytte; Krogsgaard-Larsen, Povl; Garegg, Per J.; Norberg...

Word Count : 97

Muscimol

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intended for human consumption, including muscimol. Ibotenic acid Gaboxadol Thiomuscimol CI-966 Z-drugs The Merck Index, 12th Edition "Muscimol". pubchem.ncbi...

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GABA receptor agonist

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Muscimol Phenibut Picamilon Progabide Propofol Quisqualamine SL 75102 Thiomuscimol Topiramate Zolpidem Zopiclone Alcohols (e.g., ethanol, isopropanol) Avermectins...

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Lemon balm

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 1632

Ciprofloxacin

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 6699

Baclofen

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 3270

Phenibut

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 2750

Penicillin

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 10551

Levofloxacin

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 5404

RDX

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 5940

GABA receptor antagonist

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 315

Furosemide

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 3648

Ofloxacin

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Word Count : 4449

Flumazenil

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 2416

Dehydroepiandrosterone

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 3935

Lindane

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 4059

GABA

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 5555

GABAergic

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 139

Isoflavonoid

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 242

GABA analogue

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Word Count : 754

Coriamyrtin

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Word Count : 222

Ibotenic acid

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Word Count : 1473

Thujone

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Word Count : 2621

Glutamine

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Quisqualamine SL-75102 Taurine TACA TAMP Terpenoids (e.g., borneol) Thiomuscimol Tolgabide ZAPA Positive modulators (abridged; see here for a full list):...

Word Count : 2443

Sodium oxybate

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Word Count : 4732

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