Ofloxacin is a quinolone antibiotic useful for the treatment of a number of bacterial infections.[1] When taken by mouth or injection into a vein, these include pneumonia, cellulitis, urinary tract infections, prostatitis, plague, and certain types of infectious diarrhea.[1][2] Other uses, along with other medications, include treating multidrug resistant tuberculosis.[3] An eye drop may be used for a superficial bacterial infection of the eye and an ear drop may be used for otitis media when a hole in the ear drum is present.[2]
When taken by mouth, common side effects include vomiting, diarrhea, headache, and rash.[1] Other serious side effect include tendon rupture, numbness due to nerve damage, seizures, and psychosis.[1] Use in pregnancy is typically not recommended.[4] Ofloxacin is in the fluoroquinolone family of medications.[1] It works by interfering with the bacterium's DNA.[1]
Ofloxacin was patented in 1980 and approved for medical use in 1985.[5] It is on the World Health Organization's List of Essential Medicines.[6] Ofloxacin is available as a generic medication.[1] In 2021, it was the 240th most commonly prescribed medication in the United States, with more than 1million prescriptions.[7][8]
^ abcdefg"Ofloxacin". The American Society of Health-System Pharmacists. Archived from the original on 28 December 2016. Retrieved 8 December 2016.
^ abBritish national formulary: BNF 69 (69 ed.). British Medical Association. 2015. pp. 409, 757, 782. ISBN 9780857111562.
^World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. p. 140. hdl:10665/44053. ISBN 9789241547659.
^"Ofloxacin Use During Pregnancy | Drugs.com". www.drugs.com. Archived from the original on 28 December 2016. Retrieved 28 December 2016.
^Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 500. ISBN 9783527607495. Archived from the original on 2016-12-29.
^World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
^"The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
^"Ofloxacin - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.
Ofloxacin is a quinolone antibiotic useful for the treatment of a number of bacterial infections. When taken by mouth or injection into a vein, these...
death of the bacteria. It is the left-handed isomer of the medication ofloxacin. Levofloxacin was patented in 1985 and approved for medical use in the...
sexually active are ceftriaxone and doxycycline. Among those who are older, ofloxacin may be used. Complications include infertility and chronic pain. People...
Treatment of acute cases is typically with antibiotic drops, such as ofloxacin or acetic acid. Steroid drops may be used in addition to antibiotics....
antimicrobial combination to cure single lesion paucibacillary leprosy comprises ofloxacin, rifampicin, and minocycline. Praziquantel can be useful for treating...
racemate drugs. For example, levofloxacin is a chiral switch of racemic ofloxacin. The essential principle of a chiral switch is that there is a change...
(levofloxacin), Avelox (moxifloxacin), Noroxin (norfloxacin) and Floxin (ofloxacin). On July 1, 2009, the FDA required Chantix (varenicline) to carry a boxed...
several antibiotic medications, including azithromycin, erythromycin, ofloxacin, and tetracycline. Tetracycline is the most preferred antibiotic to treat...
Antibacterial solutions include levofloxacin, gatifloxacin, moxifloxacin, ofloxacin. It is unclear if steroid eye drops are useful. In addition, contact lens...
ulcer. The molecule was identified by Daiichi Sankyo Co., which brought ofloxacin and levofloxacin to the market. Sitafloxacin is currently marketed in...
times daily for 7 days Levofloxacin 500 mg orally once daily for 7 days Ofloxacin 300 mg orally twice daily for 7 days Treatment for both gonococcal and...
and hydrocortisone; apply 3-4 drops to the affected ear 4 times daily Ofloxacin; apply 5 drops to the affected ear twice daily Ciprofloxacin with hydrocortisone;...
Guidelines recommend azithromycin, doxycycline, erythromycin, levofloxacin or ofloxacin. In men, doxycycline (100 mg twice a day for 7 days) is probably more...
Floxacin can refer to a trade name of the antibiotic ofloxacin -floxacin, the common stem of fluoroquinolone antibiotics This disambiguation page lists...
cefuroxime, amoxicillin-clavulanic acid, ciprofloxacin, enoxacin, and ofloxacin against aerobic and anaerobic bacteria isolated from bite wounds". Antimicrobial...
2012). "Comparison of doxycycline-streptomycin, doxycycline-rifampin, and ofloxacin-rifampin in the treatment of brucellosis: a randomized clinical trial"...
between two lox P sites C-Flox, abrev. for Ciprofloxacin O-Flox, abrev. for Ofloxacin FLOX, abrev. for chemotherapy protocol used in the USA (FOLFLOX in EU)...
Pediatrics. 29 (2): 181–188. PMID 1592498. Dolui SK, Das M, Hazra A (2007). "Ofloxacin-induced reversible arthropathy in a child". Journal of Postgraduate Medicine...
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