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Tet methylcytosine dioxygenase 3 information


TET3
Identifiers
AliasesTET3, hCG_40738, tet methylcytosine dioxygenase 3, BEFAHRS
External IDsOMIM: 613555; MGI: 2446229; HomoloGene: 35360; GeneCards: TET3; OMA:TET3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001287491
NM_001366022

NM_183138
NM_001347313

RefSeq (protein)

NP_001274420
NP_001352951

NP_001334242
NP_898961

Location (UCSC)Chr 2: 73.98 – 74.11 MbChr 6: 83.34 – 83.44 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tet methylcytosine dioxygenase 3 is a protein that in humans is encoded by the TET3 gene. [5]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000187605 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034832 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Tet methylcytosine dioxygenase 3". Retrieved 2018-08-13.

and 18 Related for: Tet methylcytosine dioxygenase 3 information

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Tet methylcytosine dioxygenase 3

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Tet methylcytosine dioxygenase 3 is a protein that in humans is encoded by the TET3 gene. Tet3 and its respective protein TET 3 are members of the TET...

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Tet methylcytosine dioxygenase 2

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Tet methylcytosine dioxygenase 2 (TET2) is a human gene. It resides at chromosome 4q24, in a region showing recurrent microdeletions and copy-neutral loss...

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Tet methylcytosine dioxygenase 1

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Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) is a member of the TET family of enzymes, in humans it is encoded by the TET1 gene. Its function...

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TET enzymes

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TET enzymes are a family of ten-eleven translocation (TET) methylcytosine dioxygenases. They are instrumental in DNA demethylation. 5-Methylcytosine (see...

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DNA demethylation

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are a ten-eleven translocation methylcytosine dioxygenase (TET) and thymine-DNA glycosylase (TDG). One particular TET enzyme, TET1, and TDG are present...

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Anjana Rao

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demethylation, replacement of 5-methylcytosine by cytosine. At the La Jolla Institute, her lab demonstrated the importance of TET enzymes in proper gene expression...

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Itaconic acid

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turn reduces the levels of inflammation-promoting cytokines. Tet methylcytosine dioxygenase 2 (i.e., TET2) is an enzyme that is activated by the tricarboxylic...

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CpG site

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ten-eleven translocation (TET) family of dioxygenases (TET1, TET2, TET3) to generate 5-hydroxymethylcytosine (5hmC). In successive steps TET enzymes further hydroxylate...

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Reprogramming

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central roles of ten-eleven translocation methylcytosine dioxygenases (TETs) in the demethylation of 5-methylcytosine to form cytosine. As reviewed in 2018...

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Succinic acid

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methylation. Succinate and fumarate inhibit the TET (ten-eleven translocation) family of 5-methylcytosine DNA modifying enzymes and the JmjC domain-containing...

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Epigenetics

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about 3.5-fold in DNA and this caused about 80% demethylation of the 5-methylcytosines in the genome. Demethylation of CpGs in a gene promoter by TET enzyme...

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Base excision repair

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deamination of guanine. (Thymidine products following deamination of 5-methylcytosine are more difficult to recognize, but can be repaired by mismatch-specific...

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Epigenetics in learning and memory

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in the Figure below, titled "Demethylation of 5-Methylcytosine (5mC) in neuron DNA," especially the TET dependent pathway, have been confirmed as pathways...

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Citric acid cycle

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demethylases (KDMs) and ten-eleven translocation (TET) enzymes; ordinarily TETs hydroxylate 5-methylcytosines to prime them for demethylation. However, in...

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Reactive oxygen species

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are located on chromosomes 21, 6, and 4, respectively (21q22.1, 6q25.3 and 4p15.3-p15.1). The SOD-catalysed dismutation of superoxide may be written with...

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QSER1

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(YSPTSPSYS) repeats. Interaction between homeobox protein NANOG and Tet methylcytosine dioxygenase 1 (TET1) has been shown to be important in establishing pluripotency...

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DNA oxidation

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section shows a CpG site where the cytosine is methylated to form 5-methylcytosine (5mC) and the guanine is oxidized to form 8-oxo-2'-deoxyguanosine (in...

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Expanded genetic code

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Czodrowski P, Summerer D (April 2020). "Light-Activatable TET-Dioxygenases Reveal Dynamics of 5-Methylcytosine Oxidation and Transcriptome Reorganization". Journal...

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