Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) is a member of the TET family of enzymes, in humans it is encoded by the TET1 gene. Its function, regulation, and utilizable pathways remain a matter of current research while it seems to be involved in DNA demethylation and therefore gene regulation.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000138336 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000047146 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Ten-eleven translocation methylcytosinedioxygenase1 (TET1) is a member of the TET family of enzymes, in humans it is encoded by the TET1 gene. Its function...
Tetmethylcytosinedioxygenase 2 (TET2) is a human gene. It resides at chromosome 4q24, in a region showing recurrent microdeletions and copy-neutral loss...
Tet methylcytosinedioxygenase1, or TET1, an enzyme Tetrachloride Tetrahedron Tetralogy of Fallot Tet (Morris Louis painting), a 1958 painting Tet, enormous...
Tetmethylcytosinedioxygenase 3 is a protein that in humans is encoded by the TET3 gene. Tet3 and its respective protein TET 3 are members of the TET...
TET enzymes are a family of ten-eleven translocation (TET) methylcytosinedioxygenases. They are instrumental in DNA demethylation. 5-Methylcytosine (see...
are a ten-eleven translocation methylcytosinedioxygenase (TET) and thymine-DNA glycosylase (TDG). One particular TET enzyme, TET1, and TDG are present...
demethylation, replacement of 5-methylcytosine by cytosine. At the La Jolla Institute, her lab demonstrated the importance of TET enzymes in proper gene expression...
(YSPTSPSYS) repeats. Interaction between homeobox protein NANOG and Tetmethylcytosinedioxygenase1 (TET1) has been shown to be important in establishing pluripotency...
turn reduces the levels of inflammation-promoting cytokines. Tetmethylcytosinedioxygenase 2 (i.e., TET2) is an enzyme that is activated by the tricarboxylic...
central roles of ten-eleven translocation methylcytosinedioxygenases (TETs) in the demethylation of 5-methylcytosine to form cytosine. As reviewed in 2018...
ten-eleven translocation (TET) family of dioxygenases (TET1, TET2, TET3) to generate 5-hydroxymethylcytosine (5hmC). In successive steps TET enzymes further hydroxylate...
methylation. Succinate and fumarate inhibit the TET (ten-eleven translocation) family of 5-methylcytosine DNA modifying enzymes and the JmjC domain-containing...
caused about 80% demethylation of the 5-methylcytosines in the genome. Demethylation of CpGs in a gene promoter by TET enzyme activity increases transcription...
deamination of guanine. (Thymidine products following deamination of 5-methylcytosine are more difficult to recognize, but can be repaired by mismatch-specific...
in the Figure below, titled "Demethylation of 5-Methylcytosine (5mC) in neuron DNA," especially the TET dependent pathway, have been confirmed as pathways...
demethylases (KDMs) and ten-eleven translocation (TET) enzymes; ordinarily TETs hydroxylate 5-methylcytosines to prime them for demethylation. However, in...
section shows a CpG site where the cytosine is methylated to form 5-methylcytosine (5mC) and the guanine is oxidized to form 8-oxo-2'-deoxyguanosine (in...
respectively (21q22.1, 6q25.3 and 4p15.3-p15.1). The SOD-catalysed dismutation of superoxide may be written with the following half-reactions: M ( n + 1 ) + + O 2...
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