This article may be too technical for most readers to understand. Please help improve it to make it understandable to non-experts, without removing the technical details.(January 2022) (Learn how and when to remove this message)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Nverify (what is YN ?)
Infobox references
Chemical compound
Swainsonine is an indolizidine alkaloid. It is a potent inhibitor of Golgi alpha-mannosidase II, an immunomodulator, and a potential chemotherapy drug.[1] As a toxin in locoweed (likely its primary toxin[2]) it also is a significant cause of economic losses in livestock industries, particularly in North America. It was first isolated from Swainsona canescens.[3]
Swainsonine is an indolizidine alkaloid. It is a potent inhibitor of Golgi alpha-mannosidase II, an immunomodulator, and a potential chemotherapy drug...
North America for any plant that produces swainsonine, an alkaloid harmful to livestock. Worldwide, swainsonine is produced by a small number of species...
that McCandless might have been poisoned by a toxic alkaloid called swainsonine, after eating sweet-vetch seeds (Hedysarum alpinum or Hedysarum mackenzii)...
toxic and it can be hazardous to cattle; the toxicity is related to the swainsonine produced by its endophytes, and to bioaccumulation of selenium in the...
most frequently implicated in livestock poisoning. The toxin is called swainsonine. Research suggests that the plant itself may not be toxic, but becomes...
produced as metabolites by fungi and bacteria. For instance, Slaframine and swainsonine were identified in the fungus Rhizoctonia leguminicola, while Castanospermine...
are indolizidine, which are found in a variety of alkaloids such as swainsonine. International Union of Pure and Applied Chemistry (2014). Nomenclature...
and swainsonine. "Bloat in Camelids". Croom WJ, Hagler WM, Froetschel MA, Johnson AD (May 1995). "The involvement of slaframine and swainsonine in slobbers...
a type of congestive heart failure. The toxic agent in the plant is swainsonine, an alkaloid. Animals affected include cattle, sheep, horses, goats,...
compound that forms the central core of the indolizidine alkaloids such as swainsonine and castanospermine. Indole Indolizine Tryptophan Tryptamine Skvortsov...
heterocycles have been found in nature, including deoxynojirimycin, swainsonine, australine and castanospermine. From these natural templates many other...
them to "go loco." This is caused by an alkaloid it contains called swainsonine, formerly known as locoine. The plant is toxic both fresh and dried,...
mass: 173.21 g/mol, exact mass: 173.1052 u) may refer to: Acetylleucine Swainsonine SCH-50911 This set index page lists chemical structure articles associated...
known to produce swainsonine, a phytotoxin harmful to livestock (see Locoweed). In Australia, animals intoxicated with swainsonine are said to be pea...
Global Information
verify (what is 
?)
