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Steroidal alkaloid information


Chemical structure of solanidine, a steroidal alkaloid found in potatoes

Steroidal alkaloids have the basic steroidal skeleton with nitrogen-based functional groups attached to the skeleton. More specifically, they are distinguished by their tetracyclic cyclopentanoperhydrophenanthrene skeleton that marks their close relationship with sterols.[1] They fall in two major categories: Solanum alkaloids and Veratrum alkaloids.[1] A Steroidal alkaloid has also been found in Chonemorpha fragrans (Frangipani vine), 'chonemorphine' was used to treat intestinal infections in Wistar rats. (Chatterjee DK et al (1987) Parasitol Res 74, 1, 30-33).[2]

  1. ^ a b "Steroidal Alkaloids". Pharmacognosy. July 2012. Retrieved 2018-05-05.
  2. ^ Wiart Christophe Medicinal Plants Of The Asia-pacific: Drugs For The Future (2006), p. 454, at Google Books

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Steroidal alkaloid

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Steroidal alkaloids have the basic steroidal skeleton with nitrogen-based functional groups attached to the skeleton. More specifically, they are distinguished...

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Batrachotoxin

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Batrachotoxin (BTX) is an extremely potent cardio- and neurotoxic steroidal alkaloid found in certain species of beetles, birds, and frogs. The name is...

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Alkaloid

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Overview Atta-ur-Rahman and M. Iqbal Choudhary (1997). "Diterpenoid and steroidal alkaloids". Nat. Prod. Rep. 14 (2): 191–203. doi:10.1039/np9971400191. PMID 9149410...

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Solanine

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biosynthesis of solanine, cholesterol is first converted into the steroidal alkaloid solanidine. This is accomplished through a series of hydroxylation...

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Tomatine

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lycotetraose is attached to the O-3 of the steroidal aglycone. At first it was thought that the synthesis of steroidal alkaloids only involved multiple steps of...

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Conessine

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Conessine is a steroidal alkaloid found in a number of plant species from the family Apocynaceae, including Holarrhena floribunda, Holarrhena antidysenterica...

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Steroid

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6‐dihydroergosterol in place of ergosterol in its cell membrane. Plant steroids include steroidal alkaloids found in Solanaceae and Melanthiaceae (specially the genus...

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Cyclopamine

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Cyclopamine (11-deoxojervine) is a naturally occurring steroidal alkaloid. It is a teratogenic component of corn lily (Veratrum californicum), which when...

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Saponin

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structure of a saponin can be a triterpene, a steroid (such as spirostanol or furostanol) or a steroidal alkaloid (in which nitrogen atoms replace one or more...

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Chaconine

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α-Chaconine is a steroidal glycoalkaloid that occurs in plants of the family Solanaceae. It is a natural toxicant produced in green potatoes and gives...

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Antidote

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antidote. For example, the poison batrachotoxin – a highly poisonous steroidal alkaloid derived from various poison dart frogs, certain beetles, and birds...

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Fritillaria

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flavonol glycosides and tri- and diferulic-acid sucrose esters, steroidal alkaloids, saponins and terpenoids that have formed the active ingredients...

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Veratridine

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Veratridine is a steroidal alkaloid found in plants of the lily family, specifically the genera Veratrum and Schoenocaulon. Upon absorption through the...

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Golden poison frog

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of the most poisonous animals on the planet; these frogs produce deadly alkaloid batrachotoxins in their skin glands as a defense against predators. To...

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Solasonine

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solasonine has anti-infection properties it has many adverse side effects as a steroidal glycoalkaloid. These side effects include low blood pressure, a decrease...

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Funtumia elastica

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distinctly blue due to its anthocyanin content.[citation needed] The steroidal alkaloid conessine, which is found in F. elastica, has anti-bacterial properties...

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Jervine

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Jervine is a steroidal alkaloid with molecular formula C27H39NO3 which is derived from the plant genus Veratrum. Similar to cyclopamine, which also occurs...

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Solasodine

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Solasodine is a poisonous alkaloid chemical compound that occurs in plants of the family Solanaceae such as potatoes and tomatoes. Solasonine and solamargine...

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Solanidine

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Solanidine is a poisonous steroidal alkaloid chemical compound that occurs in plants of the family Solanaceae, such as potato and Solanum americanum. Human...

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Terminaline

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Terminaline is a steroidal alkaloid isolated from Sarcococca. He, Kang; Du, Jiang (March 2010). "Two new steroidal alkaloids from the roots of". Journal...

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Cortistatins

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The cortistatins are a group of steroidal alkaloids first isolated in 2006 from the marine sponge Corticium simplex. The cortistatins were first discovered...

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Solanum aculeastrum

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Wanyonyi A.W.; Tarus P.K.; Chhabra S.C. (2003). "A novel glycosidic steroidal alkaloid from Solanum aculeastrum". Bulletin of the Chemical Society of Ethiopia...

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Zygacine

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Zygacine is a steroidal alkaloid of the genera Toxicoscordion, Zigadenus, Stenanthium and Anticlea of the family Melanthiaceae. These plants are commonly...

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Malouetine

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workers at Organon. Janot MM; Laine F; Goutarel R (1960). "Steroid alkaloids. V. Alkaloids of Malouetia bequaertiana e. Woodson (Apocynaceae): Funtuphyllamine...

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Samandarin

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Samandarin or Samandarine is the main steroidal alkaloid secreted by the fire salamander (Salamandra salamandra). The compound is extremely toxic (LD50...

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Pingbeinine

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Pingbeinine is a steroidal alkaloid isolated from Fritillaria. Two new steroidal alkaloids from Fritillaria ussuriensis v t e...

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Solamargine

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endophyte Aspergillus flavus. It is a glycoalkaloid derived from the steroidal alkaloid solasodine. Solamargine was one component of the unsuccessful experimental...

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Buxus sempervirens

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Atta-ur-Rahman, isolated a number of steroidal alkaloids from the leaves of the plant. A new system of nomenclature for buxus alkaloids was also proposed based on...

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Veratrum

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swamps, and near streambanks. Veratrum plants contain highly toxic steroidal alkaloids (e.g. veratridine) that activate sodium ion channels and cause rapid...

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Solanocapsine

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is a toxic steroidal alkaloid from Solanum pseudocapsicum (Jerusalem cherry). Barger, L. G.; Fraenkel-Conrat, H. L. (1936). "337. Alkaloids from Solanum...

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