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Chemical compound
Batrachotoxin (BTX) is an extremely potent cardio- and neurotoxic steroidal alkaloid found in certain species of beetles, birds, and frogs. The name is from the Greek word βάτραχος, bátrachos, 'frog'.[3] Structurally-related chemical compounds are often referred to collectively as batrachotoxins. In certain frogs, this alkaloid is present mostly on the skin. Such frogs are among those used for poisoning darts. Batrachotoxin binds to and irreversibly opens the sodium channels of nerve cells and prevents them from closing, resulting in paralysis and death. No antidote is known.
^ abKarle, I. L.; Karle, J. (1969). "The structural formula and crystal structure of the O-p-bromobenzoate derivative of batrachotoxinin A, C31H38NO6Br, a frog venom and steroidal alkaloid". Acta Crystallogr. B. 25 (3): 428–434. Bibcode:1969AcCrB..25..428K. doi:10.1107/S056774086900238X. PMID 5820223. S2CID 28609553.
^Daly, J. W.; Journal of the American Chemical Society 1965, V87(1), P124-6 CAPLUS
Batrachotoxin (BTX) is an extremely potent cardio- and neurotoxic steroidal alkaloid found in certain species of beetles, birds, and frogs. The name is...
pitohui, the ifrita, and the rufous or little shrikethrush all sequester batrachotoxin in their skin and feathers. The African spur-winged goose is toxic to...
variable and hooded pitohuis, contain powerful neurotoxic alkaloids of the batrachotoxin group (also secreted by the Colombian poison dart frogs, genus Phyllobates)...
Leimadophis epinephelus has shown resistance to several frog toxins including batrachotoxin, and has been observed to eat juvenile frogs without ill effects. The...
species is one of the few known poisonous birds, containing a range of batrachotoxin compounds in its skin, feathers and other tissues. These toxins are...
also known to induce a voltage-dependent open channel block on the batrachotoxin (BTX)-activated sodium channels in cardiomyocytes. Procainamide is used...
the rest of the Phyllobates species, produce a neurotoxin known as a batrachotoxin that inhibits specific transmembrane channels in cells. Due to this...
and is endemic to the Pacific coast of Colombia. Wild specimens store batrachotoxin in glands in their skin, which can be fatal to humans in doses as small...
poisonous alkaloids these frogs contain (in glands in their skin) is batrachotoxin, alongside a wide variety of other toxic compounds. Some populations...
neurotoxic alkaloid poisons in their skin. The neurotoxin is called batrachotoxin and the P. vittatius and P. ligubris are considered non-toxic because...
function of the heart using strains.[citation needed] Cardiotoxin III Batrachotoxin Heart failure Drug interaction Sishi, Balindiwe J. N. (2015-01-01),...
BTX, a popular Internet forum for fans of musician Bruce Springsteen Batrachotoxin, a neurotoxic poison that blocks sodium channels Botulinum toxin, the...
channels. Examples include toxins, such as aconitine, veratridine, batrachotoxin, robustoxin, palytoxin and ciguatoxins and insecticides (DDT and pyrethroids)...
toxins that bind to this region include the alkaloids veratridine, batrachotoxin and aconitine. Experiments using squid axonal membranes indicate that...
Melyridae family. This genus of beetle is known to have high levels of batrachotoxins and is believed to be a possible toxin source for Pitohui and Blue-capped...
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