Steatosis, also called fatty change, is abnormal retention of fat (lipids) within a cell or organ.[1] Steatosis most often affects the liver – the primary organ of lipid metabolism – where the condition is commonly referred to as fatty liver disease. Steatosis can also occur in other organs, including the kidneys, heart, and muscle.[2] When the term is not further specified (as, for example, in 'cardiac steatosis'), it is assumed to refer to the liver.[3]
Risk factors associated with steatosis are varied, and may include diabetes mellitus, protein malnutrition, hypertension,[4] cell toxins, obesity,[5] anoxia,[2] and sleep apnea.[6]
Steatosis reflects an impairment of the normal processes of synthesis and elimination of triglyceride fat. Excess lipid accumulates in vesicles that displace the cytoplasm. When the vesicles are large enough to distort the nucleus, the condition is known as macrovesicular steatosis; otherwise, the condition is known as microvesicular steatosis. While not particularly detrimental to the cell in mild cases, large accumulations can disrupt cell constituents, and in severe cases the cell may even burst.
^Ahmed MH, Byrne CD (September 2010). "Obstructive sleep apnea syndrome and fatty liver: association or causal link?". World J. Gastroenterol. 16 (34): 4243–52. doi:10.3748/wjg.v16.i34.4243. PMC 2937104. PMID 20818807.
Steatosis, also called fatty change, is abnormal retention of fat (lipids) within a cell or organ. Steatosis most often affects the liver – the primary...
Fatty liver disease (FLD), also known as hepatic steatosis and steatotic liver disease (SLD), is a condition where excess fat builds up in the liver....
elevated. These usually reflect alcoholic hepatic steatosis. Microvesicular and macrovesicular steatosis with inflammation are seen in liver biopsy specimens...
George Michael (born Georgios Kyriacos Panayiotou; 25 June 1963 – 25 December 2016) was an English singer-songwriter, record producer and philanthropist...
and consists of liver fibrosis and inflammation assessment, as well as steatosis grading. The current imaging protocol for a hepatogram is magnetic resonance...
intake of ketogenic amino acids lysine and threonine may induce hepatic steatosis, a major cause of non-alcoholic fatty liver disease. Leucine in particular...
accumulation in liver. Mere deposition of fat in the liver is termed steatosis, and together these constitute fatty liver changes. There are 2 main types...
"Increased liver echogenicity at ultrasound examination reflects degree of steatosis but not of fibrosis in asymptomatic patients with mild/moderate abnormalities...
[citation needed] Cirrhosis is often preceded by hepatitis and fatty liver (steatosis), independent of the cause. If the cause is removed at this stage, the...
disease. This ranges in order of severity and reversibility from alcoholic steatosis (least severe, most reversible), alcoholic hepatitis, cirrhosis, and liver...
available evidence indicates it does not improve outcomes of hepatic steatosis. The two contraindications to taking ezetimibe are a previous allergic...
classical effect of prolonged use both in adult and paediatric population is steatosis. Isoniazide (INH) is one of the most commonly used drugs for tuberculosis;...
syndrome in mouse models of insulin resistance; correction of hepatic steatosis in obese (ob/ob) mice; reversal of atherosclerosis in LDLR knock-out mice;...
devices might be used as point-of-care screening tools to diagnose liver steatosis. Gynecologic ultrasonography examines female pelvic organs (specifically...
are we now?. ISBN 978-953-307-883-0. El-Zayadi AR (July 2008). "Hepatic steatosis: a benign disease or a silent killer". World Journal of Gastroenterology...
IL-6 and IL-1β, in response to the increased signaling from NF-κB during steatosis. TNFα then participates in the recruitment of Kuppfer cells, which increase...
bloating Severe swelling Mouth sores or dry mouth Avascular necrosis Hepatic steatosis hiccups and burping weakening and breakage of tendons Source: Nervousness...
reduced tissue damage in the liver and spleen, prevented hepatocellular steatosis, and normalised levels of alanine aminotransferase, a liver damage marker...
acinus. Remaining viable hepatocytes frequently show ballooning injury and steatosis. The individual may experience right upper quadrant abdominal pain. The...
citrate-lactate salt, resulted in some cases of renal dysfunction, hepatic steatosis, and peripheral neuropathy in individuals using them over a long term...
fat used as pharmaceutical in traditional medicine Obesity Starvation Steatosis (also called fatty change, fatty degeneration or adipose degeneration)...
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