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Prophase information


Prophase is the first step of cell division in mitosis. As it occurs after G2 of interphase, DNA has been already replicated when prophase begins.[1]
Fluorescence microscope image of two mouse cell nuclei in prophase (scale bar is 5 μm).[2]

Prophase (from Ancient Greek προ- (pro-) 'before', and φάσις (phásis) 'appearance') is the first stage of cell division in both mitosis and meiosis. Beginning after interphase, DNA has already been replicated when the cell enters prophase. The main occurrences in prophase are the condensation of the chromatin reticulum and the disappearance of the nucleolus.[3]

  1. ^ Nussbaum RL, McInnes RR, Huntington F (2016). Thompson & Thompson Genetics in Medicine. Philadelphia: Elsevier. pp. 12–20. ISBN 9781437706963.
  2. ^ Schermelleh L, Carlton PM, Haase S, Shao L, Winoto L, Kner P, et al. (June 2008). "Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy". Science. 320 (5881): 1332–36. Bibcode:2008Sci...320.1332S. doi:10.1126/science.1156947. PMC 2916659. PMID 18535242.
  3. ^ Cite error: The named reference :2 was invoked but never defined (see the help page).

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Prophase

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Prophase (from Ancient Greek προ- (pro-) 'before', and φάσις (phásis) 'appearance') is the first stage of cell division in both mitosis and meiosis. Beginning...

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Meiosis

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replication, meiotic cells enter a prolonged G2-like stage known as meiotic prophase. During this time, homologous chromosomes pair with each other and undergo...

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Mitosis

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start of the next. These stages are preprophase (specific to plant cells), prophase, prometaphase, metaphase, anaphase, and telophase. During mitosis, the...

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Homologous chromosome

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selection to act on. In prophase I of meiosis I, each chromosome is aligned with its homologous partner and pairs completely. In prophase I, the DNA has already...

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Cell division

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not pass this checkpoint, it results in the cell exiting the cell cycle. Prophase is the first stage of division. The nuclear envelope begins to be broken...

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Oocyte

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oocytes needed for future ovulations, and these oocytes are arrested at the prophase I stage of meiosis. In humans, as an example, oocytes are formed between...

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Chromosomal crossover

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phases of genetic recombination, which occurs in the pachytene stage of prophase I of meiosis during a process called synapsis. Synapsis begins before the...

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Synaptonemal complex

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during meiosis and is thought to mediate synapsis and recombination during prophase I during meiosis in eukaryotes. It is currently thought that the SC functions...

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Interphase

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first stage of mitosis, but since mitosis is the division of the nucleus, prophase is actually the first stage. In interphase, the cell gets itself ready...

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PMAT

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monoamine transporter (PMAT) Four phases of mitosis: prophase, metaphase, anaphase, and telophase. Prophase: Chromatin into chromosomes, the nuclear envelope...

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Lampbrush chromosome

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transform into the lampbrush form during the diplotene stage of meiotic prophase I due to an active transcription of many genes. They are highly extended...

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Oogenesis

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meiotic crossing over. It then stops in early prophase. Mammalian oocytes are maintained in meiotic prophase arrest for a very long time—months in mice,...

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Zygotene

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Zygotene (from greek "paired threads") is the second stage of prophase I during meiosis, the specialized cell division that reduces the chromosome number...

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Pachytene

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"thick threads".: 27 ), also known as pachynema, is the third stage of prophase I during meiosis, the specialized cell division that reduces chromosome...

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Synapsis

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possible chromosomal crossover between them. Synapsis takes place during prophase I of meiosis. When homologous chromosomes synapse, their ends are first...

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Spermatocyte

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this is due to higher rates of degeneration of germ cells during meiotic prophase. In the following table, ploidy, copy number and chromosome/chromatid counts...

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Vertebrate

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cells of the female salamander. Synapsis and recombination during meiotic prophase I in these unisexual females is thought to ordinarily occur between identical...

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Analytical chemistry

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Fluorescence microscope image of two mouse cell nuclei in prophase (scale bar is 5 μm)...

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Preprophase

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does not occur in other eukaryotes such as animals or fungi. It precedes prophase and is characterized by two distinct events: The formation of the preprophase...

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Ovary

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follicles. Primordial follicles contain oocytes that are at an intermediate (prophase I) stage of meiosis. Meiosis is the general process in eukaryotic organisms...

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Menopause

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primary oocytes are present at an intermediate stage of meiosis, termed prophase I (see Oogenesis). Expression of four key DNA repair genes that are necessary...

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Leptotene stage

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leptotene stage, also known as leptonema, is the first of five substages of prophase I during meiosis, the specialized cell division that reduces the chromosome...

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Immature ovum

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immature ova spend most of their lifetime, more specifically in diplotene of prophase I of meiosis. The halt is called dictyate. Most degenerate by atresia,...

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Dictyate

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prolonged resting phase in oogenesis. It occurs in the stage of meiotic prophase I in ootidogenesis. It starts late in fetal life and is terminated shortly...

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Chromatid

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(homologous) chromatids form chiasmata to exchange genetic material during the prophase I of meiosis (See Homologous chromosome pair). Kinetochore Look up chromatid...

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Centromere

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believed that this complex is mostly released from chromosome arms during prophase, so that by the time the chromosomes line up at the mid-plane of the mitotic...

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WAPAL

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mitosis but lost on the arms. This removal of cohesin is known as the Prophase Pathway and results in the X-shape sister chromatids observed in chromosome...

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Cell nucleus

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most cells, the disassembly of the nuclear envelope marks the end of the prophase of mitosis. However, this disassembly of the nucleus is not a universal...

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Prometaphase

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Prometaphase is the phase of mitosis following prophase and preceding metaphase in eukaryotic somatic cells. In prometaphase, the nuclear membrane breaks...

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