Schematic of the synaptonemal complex at different stages during Prophase IA Homologous chromosomes (light blue) align and synapse together via transverse filaments (black lines) and longitudinal filaments (dark blue). Recombination nodules (gray ellipsoids) on the central region may help in completing recombination. Chromatin (red loops) is attached to its sexual leg and toe, extending from both sister chromatids. B Top: Set of tomato SCs. Chromatin "sheaths" visible around each SC. Bottom: Two tomato SCs with the chromatin removed, allowing kinetochores ("ball-like" structures) at centromeres to be revealed.
The synaptonemal complex (SC) is a protein structure that forms between homologous chromosomes (two pairs of sister chromatids) during meiosis and is thought to mediate synapsis and recombination during prophase I during meiosis in eukaryotes. It is currently thought that the SC functions primarily as a scaffold to allow interacting chromatids to complete their crossover activities.[1]
^Page SL, Hawley RS (2004-10-08). "The genetics and molecular biology of the synaptonemal complex". Annual Review of Cell and Developmental Biology. 20 (1): 525–58. doi:10.1146/annurev.cellbio.19.111301.155141. PMID 15473851.
and 26 Related for: Synaptonemal complex information
The synaptonemalcomplex (SC) is a protein structure that forms between homologous chromosomes (two pairs of sister chromatids) during meiosis and is thought...
technology, in conjunction with giesma staining can be used to image the synaptonemalcomplex throughout the various stages of meiotic prophase. To perform G-banding...
meiosis during a process called synapsis. Synapsis begins before the synaptonemalcomplex develops and is not completed until near the end of prophase I. Crossover...
associate lengthwise, facilitated by the synaptonemalcomplex protein structure. In zygotene, the synaptonemalcomplex forms more extensively between the paired...
array of loops mediated by cohesin, and the lateral elements of the synaptonemalcomplex assemble forming an "axial element" from which the loops emanate...
each other. This pairing occurs by a synapsis process where the synaptonemalcomplex – a protein scaffold – is assembled and joins the homologous chromosomes...
between achiasmate homologous chromosomes. Residual proteins from the synaptonemalcomplex (SC) ‘stick’ between the homologs' centromeres after diplotene, when...
lateral (axial) elements of the synaptonemalcomplex protein structure that forms between the homologs. The synaptonemalcomplex consists of two lateral elements...
chromosomes are fully synapsed along their lengths by the completed synaptonemalcomplex protein structure formed in the previous stages. This holds the homologs...
Synaptonemalcomplex protein 3 is a protein that in humans is encoded by the SYCP3 gene. It is a component of the synaptonemalcomplex formed between homologous...
appears to employ a Mus81-dependent pathway that does not use a synaptonemalcomplex and is considered secondary in most other model eukaryotes. This...
Synaptonemalcomplex central element protein 1 is a protein that in humans is encoded by the SYCE1 gene. Primary ovarian insufficiency can be caused by...
Synaptonemalcomplex protein SC65, also known as Leprecan-like protein 4 (LEPREL4) or nucleolar autoantigen No55, is a protein that in humans is encoded...
appears to employ a Mus81-dependent pathway that does not use a synaptonemalcomplex and is considered secondary in most other model eukaryotes. This...
Synaptonemalcomplex protein 1 is a protein involved in the synaptonemalcomplex during meiosis, that in humans is encoded by the SYCP1 gene. GRCh38: Ensembl...
ISBN 978-0-12-092860-6 Allen JW, DeWeese GK, Gibson JB, et al. (January 1987). "Synaptonemalcomplex damage as a measure of chemical mutagen effects on mammalian germ...
Genetika. 43 (5): 609–19. PMID 17633554. Carpenter, AT (2003). "Normal synaptonemalcomplex and abnormal recombination nodules in two alleles of the Drosophila...
organisms with homologous chromosomes held together only by the synaptonemalcomplex (and not crossovers) during meiosis. Kraig Biocraft Laboratories...
helicase are essential for meiotic recombination in a protist lacking a synaptonemalcomplex". Nucleic Acids Res. 41 (20): 9296–309. doi:10.1093/nar/gkt703. PMC 3814389...
protein SUPV3L1: Suv3 like RNA helicase SYCE1: encoding protein Synaptonemalcomplex central element protein 1 TACC2 encoding protein Transforming acidic...
gametocyte. AtBRCA2 protein is required for proper localization of the synaptonemalcomplex protein AtZYP1 and the recombinases AtRAD51 and AtDMC1. Furthermore...
molecules found in stress granules are stalled translation pre-initiation complexes associated with 40S ribosomal subunits, translation initiation factors...
and activates the cyclinB/cdc2 complex. Plk phosphorylates and activates components of the anaphase-promoting complex (APC). The APC, which is activated...
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