Physiological agonism describes the action of a substance which ultimately produces the same effects in the body as another substance—as if they were both agonists at the same receptor—without actually binding to the same receptor. Physiological antagonism describes the behavior of a substance that produces effects counteracting those of another substance (a result similar to that produced by an antagonist blocking the action of an agonist at the same receptor) using a mechanism that does not involve binding to the same receptor.
and 24 Related for: Physiological agonism and antagonism information
Physiologicalagonism describes the action of a substance which ultimately produces the same effects in the body as another substance—as if they were...
agonismand through α1-adrenergic receptor blockade. Overall, this vasodilatory effect can decrease blood pressure. Similar to local anesthetics and sodium...
in a spectrum from agonism to antagonism to inverse agonism. The activity of endogenous ligands (such as the hormones estradiol and testosterone) when...
and isoprenaline. Also referred to as intrinsic sympathomimetic effect, this term is used particularly with beta blockers that can show both agonism and...
binding affinity of a ligand was used to explain a mechanism of partial agonism of receptors by del Castillo & Katz in 1957 was based on their work on...
inverse agonist. Caffeine's A2A receptor inverse agonism may be the cause of the well-known physiological effects of this substance. Theophylline is a non-selective...
adenosine has a negative effect on physiological functioning by preventing necessary compensatory increases in heart rate and blood pressure that attempt to...
2016. Jane, Emma A (September 2017). "'Dude … stop the spread': antagonism, agonism, and #manspreading on social media". International Journal of Cultural...
Cdk5 (93) and NFkB (100). Moreover, many of these molecular changes identified are now directly linked to the structural, physiologicaland behavioral...
endogenous substance in which case the effect is referred to as receptor agonism (or channel or enzyme activation) or be the opposite of the endogenous...
Cdk5 (93) and NFkB (100). Moreover, many of these molecular changes identified are now directly linked to the structural, physiologicaland behavioral...
endocannabinoid system and rimonabant: a new drug with a novel mechanism of action involving cannabinoid CB1 receptor antagonism – or inverse agonism – as potential...
poorly-defined, with GABAergic, NGF and BDNF release promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma receptor agonism thought to have some involvement...
the MOR, 16 to 39% at the KOR, and 14 to 25% at the DOR in different studies. In accordance with its partial agonism, although naltrexone is described...
uptake and glucose, which is seen in clozapine and olanzapine. Other ways for dopamine to resolve is to have agonism at both the D2 receptor and 5-HT1A...
phosphatases PP1 and calcineurin. However, AMPAR endocytosis has also been activated by voltage-dependent calcium channels, agonism of AMPA receptors, and administration...
exerts its effects by agonism at this receptor is not fully understood, corresponding increased glutamatergic neurotransmission and reduced default mode...
to venlafaxine than to codeine and delivers analgesia by not only delivering "opioid-like" effects (through mild agonism of the mu receptor) but also by...
the activities are attributable to antagonism or agonism of neurotransmitters, including dopamine, serotonin and norepinephrine. He also states that...
(May 2015). "Lipid agonism: The PIP2 paradigm of ligand-gated ion channels". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids...
receptors will result in vasoconstriction and smooth muscle constriction, and the effects are similar to the agonism of alpha-1 receptors. The side effects...
Global Information