Adrenergic blocking agents are a class of drugs that exhibit its pharmacological action through inhibiting the action of the sympathetic nervous system[1] in the body. The sympathetic nervous system(SNS) is an autonomic nervous system that we cannot control by will. It triggers a series of responses after the body releases chemicals named noradrenaline and epinephrine.[1] These chemicals will act on adrenergic receptors, with subtypes Alpha-1, Alpha-2, Beta-1, Beta-2, Beta-3, which ultimately allow the body to trigger a "fight-or-flight" response to handle external stress.[1] These responses include vessel constriction in general vessels whereas there is vasodilation in vessels that supply skeletal muscles or in coronary vessels.[1] Additionally, the heart rate and contractile force increase when SNS is activated, which may be harmful to cardiac function as it increases metabolic demand.[1]
Adrenergic blocking agents treat certain diseases through blocking the adrenergic receptor,[2][3] preventing it from being activated by noradrenaline and epinephrine. As a result, it stops the body from producing the "fight-or-flight" responses.
Adrenergicblockingagents are a class of drugs that exhibit its pharmacological action through inhibiting the action of the sympathetic nervous system...
(noradrenaline) on adrenergic beta receptors, of the sympathetic nervous system, which mediates the fight-or-flight response.: 152 Some block activation of...
postsynaptic adrenergic receptor activation and downstream signaling. Another way to inhibit adrenergic receptor signaling is by blocking the synthesis...
Alpha-blockers, also known as α-blockers or α-adrenoreceptor antagonists, are a class of pharmacological agents that act as antagonists on α-adrenergic receptors...
pressure and antiasthmatic drugs. Adrenergic receptor antagonist, a type of drug blocking one or more subtypes of adrenergic receptors This mainly includes...
Ib Class Ic Class II agents are conventional beta blockers. They act by blocking the effects of catecholamines at the β1-adrenergic receptors, thereby decreasing...
of the catecholamines Sympathomimetic drugs (also known as adrenergic drugs and adrenergic amines) are stimulant compounds which mimic the effects of...
An adrenergic antagonist is a drug that inhibits the function of adrenergic receptors. There are five adrenergic receptors, which are divided into two...
An adrenergic agonist is a drug that stimulates a response from the adrenergic receptors. The five main categories of adrenergic receptors are: α1, α2...
Institute in France. Formerly investigated by Fourneau as an α-adrenergic-blockingagent, they demonstrated that it also antagonized histamine-induced...
Adrenergic neurone blockers, commonly known as adrenergic antagonists, are a group of drugs that inhibit the sympathetic nervous system by blocking the...
(September 1975). "The effect of adrenaline and of alpha- and beta-adrenergicblockingagents on ATP concentration and on incorporation of 32Pi into ATP in...
reuptake inhibitor (NRI, NERI) or noradrenaline reuptake inhibitor or adrenergic reuptake inhibitor (ARI), is a type of drug that acts as a reuptake inhibitor...
The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline)...
Kjaergaard N, Kjaergaard B, Lauritsen JG (June 1988). "Prazosin, an adrenergicblockingagent inadequate as male contraceptive pill". Contraception. 37 (6):...
A norepinephrine releasing agent (NRA), also known as an adrenergic releasing agent, is a catecholaminergic type of drug that induces the release of norepinephrine...
(intravenously) are not predictable solely by their receptor blocking effect, i.e. blocking β1-adrenergic receptors should decrease heart rate, but labetalol does...
in pregnancy and breastfeeding is not recommended. It works by blocking β1-adrenergic receptors in the heart and dilating blood vessels. Nebivolol was...
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