Part of an organism targeted by a ligand or drug to affect behavior
A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function. Examples of common classes of biological targets are proteins and nucleic acids. The definition is context-dependent, and can refer to the biological target of a pharmacologically active drug compound, the receptor target of a hormone (like insulin), or some other target of an external stimulus. Biological targets are most commonly proteins such as enzymes, ion channels, and receptors.
A biologicaltarget is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting...
The Convention on Biological Diversity (CBD), known informally as the Biodiversity Convention, is a multilateral treaty. The Convention has three main...
inventive process of finding new medications based on the knowledge of a biologicaltarget. The drug is most commonly an organic small molecule that activates...
structures, the same mechanism of action (i.e. binding to the same biologicaltarget), similar modes of action, and/or are used to treat the similar diseases...
throughput screening of large compounds libraries against isolated biologicaltargets which are hypothesized to be disease-modifying in a process known...
Druggability is a term used in drug discovery to describe a biologicaltarget (such as a protein) that is known to or is predicted to bind with high affinity...
chemical weapons, biological weapons may also be useful as area denial weapons. These agents may be lethal or non-lethal, and may be targeted against a single...
Typically the initial screening hits display binding affinities for their biologicaltarget in the micromolar (10−6 molar concentration) range. Through limited...
identify man-made objects such as ground and air vehicles as well as for biologicaltargets such as animals, humans, and vegetative clutter. This can be useful...
optimal supramolecular interactions with a specific biologicaltarget and to trigger (or block) its biological response". A pharmacophore model explains how...
Biological control or biocontrol is a method of controlling pests, whether pest animals such as insects and mites, weeds, or pathogens affecting animals...
not present in the genomes of animals. It presents an attractive biologicaltarget for herbicides, such as glyphosate. A glyphosate-resistant version...
is a highly reactive species which can directly react with various biologicaltargets and components of the cell including lipids, thiols, amino acid residues...
nonsteroidal SARM, acting as an agonist of the androgen receptor (AR), the biologicaltarget of androgens and anabolic steroids like testosterone and dihydrotestosterone...
is an AAS, and hence is an agonist of the androgen receptor, the biologicaltarget of androgens like testosterone. It is also a progestin, or a synthetic...
damage. The drug is an agonist of the androgen receptor (AR), the biologicaltarget of androgens like testosterone and dihydrotestosterone (DHT), and...
progestogen, and hence is an agonist of the progesterone receptor, the biologicaltarget of progestogens like progesterone. The medication is an atypical progestogen...
nonsteroidal SARM, acting as an agonist of the androgen receptor (AR), the biologicaltarget of androgens and anabolic steroids like testosterone and dihydrotestosterone...
anabolic steroid, hence is an agonist of the androgen receptor (AR), the biologicaltarget of androgens such as testosterone and dihydrotestosterone. Side effects...
The mammalian target of rapamycin (mTOR), also referred to as the mechanistic target of rapamycin, and sometimes called FK506-binding protein 12-rapamycin-associated...
steroid and hence is an agonist of the androgen receptor (AR), the biologicaltarget of androgens like testosterone and dihydrotestosterone (DHT). It has...
steroid and hence is an agonist of the androgen receptor (AR), the biologicaltarget of androgens like testosterone and dihydrotestosterone (DHT). It has...
Target proteins are functional biomolecules that are addressed and controlled by biologically active compounds. They are used in the processes of transduction...
(384–322 BCE) contributed extensively to the development of biological knowledge. He explored biological causation and the diversity of life. His successor, Theophrastus...
steroid and hence is an agonist of the androgen receptor (AR), the biologicaltarget of androgens like testosterone and dihydrotestosterone (DHT). Testosterone...
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