Pancreatic stellate cells (PaSCs) are classified as myofibroblast-like cells that are located in exocrine regions of the pancreas.[1]
PaSCs are mediated by paracrine and autocrine stimuli and share similarities with the hepatic stellate cell.[1] Pancreatic stellate cell activation and expression of matrix molecules constitute the complex process that induces pancreatic fibrosis.[2] Synthesis, deposition, maturation and remodelling of the fibrous connective tissue can be protective, however when persistent it impedes regular pancreatic function.[2]
^ abOmary MB, Lugea A, Lowe AW, Pandol SJ (January 2007). "The pancreatic stellate cell: a star on the rise in pancreatic diseases". J. Clin. Invest. 117 (1): 50–9. doi:10.1172/JCI30082. ISSN 0021-9738. PMC 1716214. PMID 17200706.
Pancreaticstellatecells (PaSCs) are classified as myofibroblast-like cells that are located in exocrine regions of the pancreas. PaSCs are mediated by...
Hepatic stellatecells (HSC), also known as perisinusoidal cells or Ito cells (earlier lipocytes or fat-storing cells), are pericytes found in the perisinusoidal...
Kupffer cells, also known as stellate macrophages and Kupffer–Browicz cells, are specialized cells localized in the liver within the lumen of the liver...
Human Cell Atlas project, which started in 2016, had as one of its goals to "catalog all cell types (for example, immune cells or brain cells) and sub-types...
The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869...
progenitor cells are precursor cells that differentiate into the functional pancreaticcells, including exocrine acinar cells, endocrine islet cells, and ductal...
Pacific Science Center, a science museum in Seattle, Washington Pancreaticstellatecell Pediatric Symptom Checklist, a psychological assessment tool Phylogenetic...
COVID PASC audio compression, a version of MPEG-1 Audio Layer I Pancreaticstellatecell (PaSC) Portable Applications Standards Committee, of the IEEE Computer...
The pancreatic duct or duct of Wirsung (also, the major pancreatic duct due to the existence of an accessory pancreatic duct) is a duct joining the pancreas...
Isolation of Hepatic stellatecells: Shang L, Hosseini M, Liu X, Kisseleva T, Brenner DA (January 2018). "Human hepatic stellatecell isolation and characterization"...
cells can take up and destroy foreign material such as bacteria. Hepatocytes are separated from the sinusoids by the space of Disse. Hepatic stellate...
endothelial cells, and phagocytic Kupffer cells. Hepatic stellatecells are nonparenchymal cells found in the perisinusoidal space, between a sinusoid and...
interleukin-13 and interleukin-6 on Jak/STAT signaling and cell viability in pancreatic β-cells". Islets. 5 (2): 95–105. doi:10.4161/isl.24249. ISSN 1938-2014...
Kupffer cells are scattered between endothelial cells; they are part of the reticuloendothelial system and phagocytose spent erythrocytes. Stellate (Ito)...
cells and duct cells.They represent an extension of the intercalated duct into each pancreatic acinus. .These cells are commonly known as duct cells,...
upregulated in the tumor stroma of pancreatic ductal adenocarcinoma. Knocking down of ITGA11 in human pancreaticstellatecells led to the inhibition of their...
the Pancreatic Research Group at the University of South Wales which is credited as the first research group to describe pancreaticstellatecells. Pirola...
field of pancreatic disease research, including becoming the first in the world to successfully isolate pancreaticstellatecells (PSCs), the cells associated...
differentiation of a fibroblastic cell Activation of a stellatecell (e.g. hepatic Ito cells or pancreaticstellatecells). Loss of contractile phenotype...
macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellatecells in mice". Hepatology. 58 (4):...
lodges in the biliary system, jaundice may occur; if the stone blocks the pancreatic duct, pancreatitis may occur. Gallstones are diagnosed using ultrasound...
duct that is usually formed by a union of the common bile duct and the pancreatic duct within the wall of the duodenum. This common duct usually features...
bilirubin. The perisinusoidal space also contains hepatic stellatecells (also known as Ito cells), which store fat or fat soluble vitamins including vitamin...
specialised cells of the GI tract. These include the various cells of the gastric glands, taste cells, pancreatic duct cells, enterocytes and microfold cells. Some...
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