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POU domain information


Pou domain - N-terminal to homeobox domain
Identifiers
SymbolPou
PfamPF00157
InterProIPR000327
PROSITEPDOC00035
SCOP21oct / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

POU (pronounced 'pow') is a family of eukaryotic transcription factors that have well-conserved homeodomains.[1] The Pou domain is a bipartite DNA binding domain found in these proteins.

  1. ^ Phillips K, Luisi B (Oct 2000). "The virtuoso of versatility: POU proteins that flex to fit". Journal of Molecular Biology. 302 (5): 1023–39. doi:10.1006/jmbi.2000.4107. PMID 11183772.

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POU domain

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POU (pronounced 'pow') is a family of eukaryotic transcription factors that have well-conserved homeodomains. The Pou domain is a bipartite DNA binding...

Word Count : 999

POU

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Look up pou, Pou, póu, pòu, põu, pōu, pǒu, or pɔu in Wiktionary, the free dictionary. POU or pou may refer to: Pou (surname), a surname Chu Pou (303–350)...

Word Count : 155

POU2F1

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POU domain, class 2, transcription factor 1 is a protein that in humans is encoded by the POU2F1 gene. POU2F1 has been shown to interact with: EPRS, Glucocorticoid...

Word Count : 1916

Homeobox

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The individual domains of POU proteins bind DNA only weakly, but have strong sequence-specific affinity when linked. The POU domain itself has significant...

Word Count : 4469

POU4F1

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POU domain, class 4, transcription factor 1 (POU4F1) also known as brain-specific homeobox/POU domain protein 3A (BRN3A), homeobox/POU domain protein...

Word Count : 2159

POU3F2

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POU domain, class 3, transcription factor 2 is a protein that in humans is encoded by the POU3F2 gene. N-Oct-3 is a protein belonging to a large family...

Word Count : 1170

DMRT1

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family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining...

Word Count : 1641

POU3F1

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POU domain, class 3, transcription factor 1 (also known as Oct-6) is a protein that in humans is encoded by the POU3F1 gene. Octamer transcription factor...

Word Count : 780

Transcription factor

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Class: Homeo domain 3.1.1 Family: Homeo domain only; includes Ubx 3.1.2 Family: POU domain factors; includes Oct 3.1.3 Family: Homeo domain with LIM region...

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POU4F2

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POU domain, class 4, transcription factor 2 is a protein that in humans is encoded by the POU4F2 gene. POU4F2 is a member of the POU-domain family of...

Word Count : 988

SPRM

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SPRM may refer to: Sprm1, a POU domain protein also known as POU5F2 Selective progesterone receptor modulator Surface plasmon resonance microscopy Malaysian...

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Nuclear receptor

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(F) domains may be conformationally flexible and disordered. Domains relative orientations are very different by comparing three known multi-domain crystal...

Word Count : 6675

Zinc finger

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Krüppel factor in Drosophila. It often appears as a metal-binding domain in multi-domain proteins. Proteins that contain zinc fingers (zinc finger proteins)...

Word Count : 4825

POU2F3

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POU domain, class 2, transcription factor 3 is a protein that in humans is encoded by the POU2F3 gene. GRCh38: Ensembl release 89: ENSG00000137709 – Ensembl...

Word Count : 523

POU4F3

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POU domain, class 4, transcription factor 3 is a protein that in humans is encoded by the POU4F3 gene. It's a member of BRN-3 group, also known as POU...

Word Count : 561

Octamer transcription factor

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DNA-binding domain is a POU domain. There are eight Octamer proteins in humans (Oct1–11), which have been renamed according to the different classes of POU domain...

Word Count : 281

Androgen receptor

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antagonists). Inhibitors that target alternative functional domains (N-terminal domain, DNA-binding domain) of the protein are still under development. Alteration...

Word Count : 9673

POU2AF1

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POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene. The protein is also termed Oct coactivator from B cells...

Word Count : 1482

BZIP domain

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The Basic Leucine Zipper Domain (bZIP domain) is found in many DNA binding eukaryotic proteins. One part of the domain contains a region that mediates...

Word Count : 663

Nono

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PreCure Nono Ichinose, a character in the manga Hitohira NONO or Non-POU domain-containing octamer-binding protein, a protein that in humans is encoded...

Word Count : 452

FOX proteins

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butterfly-like appearance of the loops in the protein structure of the domain. Forkhead proteins are a subgroup of the helix-turn-helix class of proteins...

Word Count : 874

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