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Nucleotide exchange factor information


Movie of ELMO-YFP recruitment to sites of attached anti-ICAM-1 beads on TNF-α-treated MAECs isolated from SGEF−/− animals. The arrow indicates the location on an attaching anti-ICAM-1 bead.

Nucleotide exchange factors (NEFs) are proteins that stimulate the exchange (replacement) of nucleoside diphosphates for nucleoside triphosphates bound to other proteins.

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Nucleotide exchange factor

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Nucleotide exchange factors (NEFs) are proteins that stimulate the exchange (replacement) of nucleoside diphosphates for nucleoside triphosphates bound...

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Guanine nucleotide exchange factor

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Guanine nucleotide exchange factors (GEFs) are proteins or protein domains that activate monomeric GTPases by stimulating the release of guanosine diphosphate...

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GrpE

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GrpE (Gro-P like protein E) is a bacterial nucleotide exchange factor that is important for regulation of protein folding machinery, as well as the heat...

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SOS1

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that in humans is encoded by the SOS1 gene. SOS1 is a guanine nucleotide exchange factor (GEF) which interacts with Ras proteins to phosphorylate GDP into...

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RAPGEF3

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nucleotide exchange factor 3 also known as exchange factor directly activated by cAMP 1 (EPAC1) or cAMP-regulated guanine nucleotide exchange factor I...

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Nerve growth factor

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G-protein known as Ras. The guanine nucleotide exchange factor mediates Ras activation through the GDP-GTP exchange process. The active Ras protein phosphorylates...

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KRAS

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proteins of the Guanine Nucleotide Exchange Factor (GEF) class (such as SOS1), which forces the release of bound nucleotide (GDP). Subsequently, KRAS...

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ARHGEF6

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Rho guanine nucleotide exchange factor 6 is a protein that, in humans, is encoded by the ARHGEF6 gene. ARHGEF6 is commonly known as the p21-activated protein...

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Housekeeping gene

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Rho guanine nucleotide exchange factor 10L ARHGEF11 Rho guanine nucleotide exchange factor 11 ARHGEF40 Rho guanine nucleotide exchange factor 40 ARHGEF7...

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SIL1

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Nucleotide exchange factor SIL1 is a protein that in humans is encoded by the SIL1 gene. This gene encodes a resident endoplasmic reticulum (ER), N-linked...

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HRAS

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proteins of the Guanine Nucleotide Exchange Factor (GEF) class, for example SOS1, which forces the release of bound nucleotide. Subsequently, GTP present...

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FGD1

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FYVE domain-containing protein 3 (ZFYVE3), or Rho/Rac guanine nucleotide exchange factor FGD1 (Rho/Rac GEF) is a protein that in humans is encoded by the...

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RCC1

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guanine nucleotide exchange factor and RanGEF, is the name for a human gene and protein. RCC1 also functions as a guanine nucleotide exchange factor for Ran...

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SGEF

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nucleotide Exchange Factor) is a 97 kDa protein involved in intracellular signalling networks. It functions as a guanine nucleotide exchange factor (GEF)...

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GEF

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Korean War Greif, Inc., an American manufacturing company Guanine nucleotide exchange factor This disambiguation page lists articles associated with the title...

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GEFT

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S2CID 2418867. Bryan BA, Cai Y, Liu M (2006). "The Rho-family guanine nucleotide exchange factor GEFT enhances retinoic acid- and cAMP-induced neurite outgrowth"...

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VAV2

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Guanine nucleotide exchange factor VAV2 is a protein that in humans is encoded by the VAV2 gene. VAV2 is the second member of the VAV oncogene family....

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RASGRF2

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inactive GDP-bound state and an active GTP-bound state. Guanine-nucleotide exchange factors (GEFs), such as RASGRFs, stimulate the conversion of the GDP-bound...

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C9orf72

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associated with amyotrophic lateral sclerosis (ALS) is a guanine nucleotide exchange factor". PeerJ. 6: e5815. doi:10.7717/peerj.5815. PMC 6195791. PMID 30356970...

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RAPGEF6

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Rap guanine nucleotide exchange factor 6 is a protein that in humans is encoded by the RAPGEF6 gene. GRCh38: Ensembl release 89: ENSG00000158987 – Ensembl...

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EIF2B

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complex found in eukaryotes. It is the guanine nucleotide exchange factor for the eukaryotic initiation factor 2 and therefore converts the inactive eIF2-GDP...

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CYTH2

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Hansen SH, Casanova JE (1998). "ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6". J. Biol. Chem. 273 (1): 23–7. doi:10.1074/jbc...

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ARHGEF12

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Leukemia-associated Rho guanine nucleotide exchange factor (LARG). Rho guanine nucleotide exchange factor 12 is guanine nucleotide exchange factor (GEF) for the RhoA...

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GBF1

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Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the GBF1 gene. GRCh38: Ensembl release...

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RAPGEF4

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Rap guanine nucleotide exchange factor (GEF) 4 (RAPGEF4), also known as exchange protein directly activated by cAMP 2 (EPAC2) is a protein that in humans...

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