Regulator of chromosome condensation 1, also known as RCC1, Ran guanine nucleotide exchange factor and RanGEF, is the name for a human gene and protein.[5]
RCC1 also functions as a guanine nucleotide exchange factor for Ran GTPase.
^ abcGRCh38: Ensembl release 89: ENSG00000180198 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000028896 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: RCC1 Regulator of chromosome condensation 1".
condensation 1, also known as RCC1, Ran guanine nucleotide exchange factor and RanGEF, is the name for a human gene and protein. RCC1 also functions as a guanine...
factor for the small GTPase Ran (Regulator of chromosome condensation 1 or RCC1) is attached to nucleosomes via core histones H2A and H2B. Thus, a gradient...
the opposite function of the RCC1, a nuclear-located protein that converts RanGDP to RanGTP. Together, RanGAP and RCC1 maintain what is known as the...
of RCC1 to histone proteins H2A and H2B. The RCC1-chromatin interaction is also an example of a protein-DNA interaction, as another domain of RCC1 interacts...
Ran GEF, RCC1, is present in the nucleus while the Ran GAP is present in the cytosol, modulating nuclear import and export of proteins. RCC1 converts...
RCC1 and BTB domain-containing protein 2 is a protein that in humans is encoded by the RCBTB2 gene. This gene encodes a member of the RCC1-related GEF...
mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. RANBP1 has been...
kDa (TD-60) or RCC1-like protein TD-60 is a protein that in humans is encoded by the RCC2 gene. RCC2 has structural similarity to RCC1, and has been shown...
encodes large protein products with C-terminal HECT domains and one or more RCC1-like (RLD) domains. HERC2, previously referred to as the rjs gene locus,...
osteosarcoma) RCBTB1: encoding protein RCC1 and BTB domain-containing protein 1 RCBTB2: encoding protein RCC1 and BTB domain-containing protein 2 RGCC:...
may be homologous to another protein involved in chromatin condensation, RCC1. CENP-E is a 312kDa protein from the kinesin motor protein family. CENP-F...
(August 1998). "Identification of a large Myc-binding protein that contains RCC1-like repeats". Proceedings of the National Academy of Sciences of the United...
RCC1 and BTB domain-containing protein 1 is a protein that in humans is encoded by the RCBTB1 gene. This gene encodes a protein with an N-terminal RCC1...
family of ubiquitin ligases and encodes a protein with a HECT domain and an RCC1-like domain (RLD). It binds ubiquitin and hPLIC-1/2 via its HECT domain....
family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in...
identified the gene, RCC1, that made the protein. Nishimoto first sent a postdoctoral researcher, Hideo Nishitani, to conduct RCC1 experiments in Newport's...
And CCCH-Type Domains 1 RC3H2 MNAB Ring Finger And CCCH-Type Domains 2 RCC1RCC1 Regulator of chromosome condensation RCC2 RCC2 Protein RCC2 RECQL RECQL1...
Ohtsubo M (December 1999). "A novel human gene encoding HECT domain and RCC1-like repeats interacts with cyclins and is potentially regulated by the tumor...
"p619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteins". EMBO J...
proteins involved in regulating chromatin condensation, for example the human RCC1 gene product. In the dark state, UVR8 forms a homodimer that is localized...
but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The...
between the two segments. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide...
isoforms, have been characterized. RANBP3 has been shown to interact with RCC1 and XPO1. GRCh38: Ensembl release 89: ENSG00000031823 – Ensembl, May 2017...
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