Neurophysin I is a carrier protein with a size of 10 KDa and contains 90 to 97 amino acids. It is a cleavage product (formed by splitting of a compound molecule into a simpler one) of preprooxyphysin.[1] It is a neurohypophysial hormone that is transported in vesicles with oxytocin, the other cleavage product, along axons, from magnocellular neurons of the hypothalamus to the posterior lobe of the pituitary. Although it is stored in neurosecretory granules with oxytocin and released with oxytocin, its biological action is unclear.
^Rao VV, Löffler C, Battey J, Hansmann I (1992). "The human gene for oxytocin-neurophysin I (OXT) is physically mapped to chromosome 20p13 by in situ hybridization". Cytogenet. Cell Genet. 61 (4): 271–3. doi:10.1159/000133420. PMID 1486803.
NeurophysinI is a carrier protein with a size of 10 KDa and contains 90 to 97 amino acids. It is a cleavage product (formed by splitting of a compound...
neurosecretory granules, the analogous neurophysinI and II form stabilizing complexes via covalent interactions. Stabilizing neurophysin-hormone complexes that are...
carrier protein neurophysinI. The inactive precursor protein is progressively hydrolyzed into smaller fragments (one of which is neurophysinI) via a series...
Neurophysin II is a carrier protein with a size of 19,687.3 Da and is made up of a dimer of two virtually identical chains of amino acids. Neurophysin...
contains ATP and a type of neurophysin. Neurophysins are binding proteins, of which there are two types: neurophysinI and neurophysin II, which bind to oxytocin...
hypothalamo-neurohypophyseal tract with the help of the carrier protein, neurophysinI, to the pars nervosa of the posterior pituitary, and then stored in...
thus allowing water reabsorption and excretion of more concentrated urine, i.e., antidiuresis. This occurs through increased transcription and insertion...
carbonate taken two to three times daily is typical for maintenance of bipolar I disorder in adults, where the exact dose given varies depending on factors...
is denser in a Type I synapse than it is in a Type II, and the Type I synaptic cleft is wider. Finally, the active zone on a Type I synapse is larger than...
Frankfurt/Main, 2017, Aufl. 57, ISBN 978-3-946057-10-9, S. 222. Gheorghiade M, Niazi I, Ouyang J, et al. (2003). "Vasopressin V2-receptor blockade with tolvaptan...
1016/j.tips.2018.11.001. PMID 30509888. S2CID 54559394. Viero C, Shibuya I, Kitamura N, Verkhratsky A, Fujihara H, Katoh A, Ueta Y, Zingg HH, Chvatal...
tegmental area (VTA) dopaminergic neurons that project to the nucleus accumbens, i.e., the mesolimbic pathway. Activation of the PVN→VTA projection by oxytocin...
channel antagonists, it was no better than placebo in the major outcomes i.e. pregnancy prolongation or neonatal outcomes. The finding of an increase...
Uzefovsky F, Cohen L, Feldman E, Lerer E, Laiba E, Raz Y, Nemanov L, Gritsenko I, Dina C, Agam G, Dean B, Bornstein G, Ebstein RP (Apr 2008). "Individual differences...
mainstay of treatment for euvolemic (i.e., SIADH, postoperative hyponatremia) and hypervolemic hyponatremia (i.e., CHF and cirrhosis). V2RAs predictably...
Deteclo, Detravis, Meciclin, Mexocine, and Clortetrin.[citation needed] Chopra I, Hawkey PM, Hinton M (March 1992). "Tetracyclines, molecular and clinical...
Development of Oxytocin-Based Therapeutics for Brain Disorders". In Shalev I, Ebstein RP (eds.). Social Hormones and Human Behavior: What Do We Know and...
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