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Neurophysin I information


Neurophysin I
Identifiers
AliasesOxytocin Associated NeurophysinOxytocin-Associated Neurophysin
External IDsGeneCards: [1]; OMA:- orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
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Neurophysin I is a carrier protein with a size of 10 KDa and contains 90 to 97 amino acids. It is a cleavage product (formed by splitting of a compound molecule into a simpler one) of preprooxyphysin.[1] It is a neurohypophysial hormone that is transported in vesicles with oxytocin, the other cleavage product, along axons, from magnocellular neurons of the hypothalamus to the posterior lobe of the pituitary. Although it is stored in neurosecretory granules with oxytocin and released with oxytocin, its biological action is unclear.

  1. ^ Rao VV, Löffler C, Battey J, Hansmann I (1992). "The human gene for oxytocin-neurophysin I (OXT) is physically mapped to chromosome 20p13 by in situ hybridization". Cytogenet. Cell Genet. 61 (4): 271–3. doi:10.1159/000133420. PMID 1486803.

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