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Myoglobinuria information


Myoglobinuria
Urine from a person with rhabdomyolysis showing the characteristic brown discoloration as a result of myoglobinuria
SpecialtyNephrology

Myoglobinuria is the presence of myoglobin in the urine, which usually results from rhabdomyolysis or muscle injury.[1] Myoglobin is present in muscle cells as a reserve of oxygen.

  1. ^ Prasad Devarajan, MD, FAAP (2020-02-19). "Myoglobinuria: Background, Pathophysiology, Etiology". Medscape Reference. Retrieved 2020-07-13. Myoglobinuria is usually the result of rhabdomyolysis or muscle destruction. When excreted into the urine, myoglobin, a monomer containing a heme molecule similar to hemoglobin, can precipitate, causing tubular obstruction and acute kidney injury.{{cite web}}: CS1 maint: multiple names: authors list (link)

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Myoglobinuria

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Myoglobinuria is the presence of myoglobin in the urine, which usually results from rhabdomyolysis or muscle injury. Myoglobin is present in muscle cells...

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Rhabdomyolysis

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quantity of myoglobin exceeds the binding capacity of haptoglobin. Myoglobinuria, the presence of myoglobin in the urine, occurs when the level in plasma...

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Cytochrome c oxidase subunit I

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deficiency, colorectal cancer, sensorineural deafness, and recurrent myoglobinuria. In humans, the MT-CO1 gene is located from nucleotide pairs 5904 to...

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Hemoglobinuria

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microscopically despite a positive dipstick test suggests hemoglobinuria or myoglobinuria. The medical term for RBCs in the urine is hematuria. Hematuria Deters...

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Metabolic myopathy

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or pseudohypertrophy) especially of the calves, reddish-brown urine (myoglobinuria) and considerable breakdown of muscle tissue (rhabdomyolysis). The degree...

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Lactate dehydrogenase

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Mutations of the M subunit have been linked to the rare disease exertional myoglobinuria (see OMIM article), and mutations of the H subunit have been described...

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Glycogen storage disease type V

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previous episodes of myoglobinuria and 6.8% had normal CK (including those with fixed muscle weakness); so an absence of myoglobinuria and normal CK should...

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Cytochrome c oxidase subunit III

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optic neuropathy, mitochondrial complex IV deficiency, and recurrent myoglobinuria . The MT-CO3 gene produces a 30 kDa protein composed of 261 amino acids...

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Proteinuria

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Interstitial nephritis Sickle cell disease Hemoglobinuria Multiple myeloma Myoglobinuria Organ rejection: Ebola virus disease Nail–patella syndrome Familial...

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Urinalysis

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cells (hematuria), free hemoglobin (hemoglobinuria), or myoglobin (myoglobinuria). Red blood cells can sometimes be distinguished from free hemoglobin...

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Hitting the wall

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synthesis). Severe breakdown of muscle leads to rhabdomyolysis and myoglobinuria. Excessive use of the myokinase reaction and purine nucleotide cycle...

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Carnitine palmitoyltransferase II deficiency

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males. CPT II deficiency is also the most frequent cause of hereditary myoglobinuria. The three main types of carnitine palmitoyltransferase II deficiency...

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Glycogen storage disease

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pseudoathletic appearance of hypertrophic calf muscles. Renal failure by myoglobinuria, second wind phenomenon, inappropriate rapid heart rate (sinus tachycardia)...

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Urine test strip

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provided that correspond to the reactions that occur with hemoglobinuria, myoglobinuria and hematuria (RBCs). In the presence of free hemoglobin/myoglobin,...

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Phosphofructokinase 1

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muscle weakness (myopathy) and exercise induced cramping and spasms, myoglobinuria (presence of myoglobin in urine, indicating muscle destruction) and...

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Exercise intolerance

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with Exercise-induced Vissing, John (2016). "Exercise intolerance and myoglobinuria". In Lisak, Robert P.; Truong, Daniel D.; Carroll, William M.; Bhidayasiri...

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Cocaine intoxication

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hyperthermia may cause muscle cell destruction (rhabdomyolysis) and myoglobinuria resulting in kidney failure. Individuals with cocaine overdose should...

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Second wind

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synthesis). Severe breakdown of muscle leads to rhabdomyolysis and myoglobinuria. Excessive use of the myokinase reaction and purine nucleotide cycle...

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Coniine

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Lesbos who also consumed quail suffered from the same poisoning, causing myoglobinuria and acute kidney injury. The most famous hemlock poisoning occurred...

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Benign acute childhood myositis

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of a high level of creatine kinase suggests the diagnosis of BACM. Myoglobinuria is rare and points to the possibility of the development of rhabdomyolysis...

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Microhematuria

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Urological Association guidelines were updated. Proteinuria Hematuria Myoglobinuria Hemoglobinuria "Sickle Cell trait and Hematuria: Information for healthcare...

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Equine atypical myopathy

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Equine atypical myopathy, also known as atypical myoglobinuria, or EAM is a fatal disease of horses (equidae) characterized by acute rhabdomyolysis. It...

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Inborn errors of carbohydrate metabolism

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some rhabdomyolysis and myoglobinuria. Liver symptoms: Hepatomegaly RBC symptoms: Hemolytic anemia. Rhabdomyolysis/myoglobinuria may cause acute renal failure...

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Mitochondrial myopathy

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intolerance manifesting as exercise-induced myalgia, muscle stiffness, myoglobinuria and rhabdomyolysis. A few Limb–girdle muscular dystrophies are known...

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Inland taipan

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their muscles release myoglobin, which is passed through the kidneys (myoglobinuria). The kidneys are often badly damaged by filtering so much tissue debris...

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Statin

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Henderson R (20 January 2015). "Rhabdomyolysis and Other Causes of Myoglobinuria". Archived from the original on 7 May 2015. Retrieved 6 May 2015. Mendes...

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Myoglobin

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assemblies. Cytoglobin Hemoglobin Hemoprotein Neuroglobin Phytoglobin Myoglobinuria - The presence of myoglobin in the urine Ischemia-reperfusion injury...

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Myopathy

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myositis (M61) Myositis ossificans (M62.89) Rhabdomyolysis and (R82.1) myoglobinurias The Food and Drug Administration is recommending that physicians restrict...

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