Lactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells. LDH catalyzes the conversion of pyruvate to lactate and back, as it converts NAD+ to NADH and back. A dehydrogenase is an enzyme that transfers a hydride from one molecule to another.
LDH exists in four distinct enzyme classes. This article is specifically about the NAD(P)-dependent L-lactate dehydrogenase. Other LDHs act on D-lactate and/or are dependent on cytochrome c: D-lactate dehydrogenase (cytochrome) and L-lactate dehydrogenase (cytochrome).
LDH is expressed extensively in body tissues, such as blood cells and heart muscle. Because it is released during tissue damage, it is a marker of common injuries and disease such as heart failure.
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Lactatedehydrogenase (LDH or LD) is an enzyme found in nearly all living cells. LDH catalyzes the conversion of pyruvate to lactate and back, as it converts...
Lactatedehydrogenase A (LDHA) is an enzyme which in humans is encoded by the LDHA gene. It is a monomer of Lactatedehydrogenase, which exists as a tetramer...
lactate dehydrogenase (LDH) complex and decreases the activity of lactatedehydrogenase A (LDHA), while increasing the activity of lactatedehydrogenase B (LDHB)...
pregnant women. In contrast to ALP, levels of ALT, AST, GGT, and lactatedehydrogenase are only slightly changed or largely unchanged during pregnancy...
kinase (PK), pyruvate dehydrogenase kinase, isozyme 1 (PDK1) and lactatedehydrogenase A (LDH-A). In addition to alterations in oxygen concentration associated...
sarx, meaning "flesh". In animals, L-lactate is constantly produced from pyruvate via the enzyme lactatedehydrogenase (LDH) in a process of fermentation...
dehydrogenases: The malate dehydrogenase family contains L-lactatedehydrogenase and L-2-hydroxyisocaproate dehydrogenases. L-lactatedehydrogenases catalyzes...
the fermentation will happen anyway. Lactatedehydrogenase catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH...
converted by fermentation to lactate using the enzyme lactatedehydrogenase and the coenzyme NADH in lactate fermentation, or to acetaldehyde (with the enzyme...
Lactatedehydrogenase B is a protein that in humans is encoded by the LDHB gene. This gene encodes the B subunit of lactatedehydrogenase enzyme, which...
Lactatedehydrogenase elevating virus (LDV) constitutes the species Gamamaarterivirus lacdeh which is part of the family Arteriviridae and order Nidovirales...
In Toxoplasma gondii the translational repression of lactatedehydrogenase 1 (LDH1) was discovered to be mediated through its 5′UTR. A small nucleotide...
by the pyruvate dehydrogenase complex. Pyruvate dehydrogenase deficiency can be diagnosed via the following methods: Blood test (Lactate and pyruvate levels)...
based on blood tests finding signs of red blood cell breakdown (lactatedehydrogenase greater than 600 U/L), an aspartate transaminase greater than 70...
the "A" isoform of the enzyme lactatedehydrogenase (LDHA), which predominantly converts pyruvate into lactate. The lactate is carried by the bloodstream...
enzyme lactatedehydrogenase. Oxamate is a possible pyruvate analog that has the ability to halt lactate production by inhibiting lactatedehydrogenase, effectively...
different energy sources: formate dehydrogenase, lactatedehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, H2 dehydrogenase (hydrogenase), electron transport...
normally sequestered inside cells to the outside. One molecule, lactatedehydrogenase (LDH), is commonly measured using LDH assay. LDH reduces NAD to...
from NADH by reduction of pyruvate to lactate. Lactate is converted to pyruvate by the enzyme lactatedehydrogenase. The standard free energy change of...
related to the variability in the target antigen. P. falciparum lactatedehydrogenase (PfLDH) is a 33 kDa oxidoreductase [EC 1.1.1.27]. It is the last...
dehydrogenase glutamate dehydrogenase (an enzyme that can convert glutamate to α-Ketoglutarate and vice versa). lactatedehydrogenase (used to convert NADH...
is converted to lactate (the conjugate base of lactic acid) in a process called lactic acid fermentation: Pyruvate + NADH + H+ → Lactate + NAD+ This process...
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