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Monoclonal gammopathy information


Monoclonal gammopathy
Other namesparaproteinemia
Serum protein electrophoresis shows gamma spike, or peak
SpecialtyOncology Edit this on Wikidata

Monoclonal gammopathy, also known as paraproteinemia, is the presence of excessive amounts of myeloma protein or monoclonal gamma globulin in the blood. It is usually due to an underlying immunoproliferative disorder or hematologic neoplasms, especially multiple myeloma. It is sometimes considered equivalent to plasma cell dyscrasia. The most common form of the disease is monoclonal gammopathy of undetermined significance.

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Monoclonal gammopathy

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Monoclonal gammopathy, also known as paraproteinemia, is the presence of excessive amounts of myeloma protein or monoclonal gamma globulin in the blood...

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Monoclonal gammopathy of undetermined significance

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Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia in which plasma cells or other types of antibody-producing cells...

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Monoclonal gammopathy of renal significance

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Monoclonal gammopathy of renal significance (MGRS) are a group of kidney disorders that present with kidney damage due to nephrotoxic monoclonal immunoglobulins...

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POEMS syndrome

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fibre sensory modalities. Plasma cell dyscrasias are a group of monoclonal gammopathies in which normal plasma cells in the bone marrow and soft tissues...

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Plasma cell dyscrasias

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proliferative diseases) are a spectrum of progressively more severe monoclonal gammopathies in which a clone or multiple clones of pre-malignant or malignant...

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Myeloma protein

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produced in excess by an abnormal monoclonal proliferation of plasma cells, typically in multiple myeloma or Monoclonal gammopathy of undetermined significance...

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Serum protein electrophoresis

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electrophoresis test are to diagnose or monitor multiple myeloma, a monoclonal gammopathy of uncertain significance (MGUS), or further investigate a discrepancy...

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Multiple myeloma

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causation of multiple myeloma. Multiple myeloma may develop from monoclonal gammopathy of undetermined significance (MGUS) that progresses to smoldering...

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Gamma globulin

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hypogammaglobulinemia. A disease of gamma globulins is called a "gammopathy" (for example, in monoclonal gammopathy of undetermined significance). Brutton's agammaglobulinemia...

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Precancerous condition

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include certain colon polyps, which can progress into colon cancer, monoclonal gammopathy of undetermined significance, which can progress into multiple myeloma...

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Smouldering myeloma

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secreting monoclonal paraprotein (also termed myeloma protein or M protein) causes the relatively benign disease of monoclonal gammopathy of undetermined...

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Capillary leak syndrome

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August 2022). "Management of Acute Episodes of Clarkson Disease (Monoclonal Gammopathy-Associated Systemic Capillary Leak Syndrome) With Intravenous Immunoglobulins"...

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Pyoderma gangrenosum

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Myelocytic leukemia Hairy cell leukemia Myelofibrosis Myeloid metaplasia Monoclonal gammopathy Solid tumors A rare syndromic association called pyogenic arthritis...

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Chronic inflammatory demyelinating polyneuropathy

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polyneuropathy (CIDP) with subtypes: Classical CIDP CIDP with diabetes CIDP/monoclonal gammopathy of undetermined significance Sensory CIDP Multifocal motor neuropathy...

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Monoclonal immunoglobulin deposition disease

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abnormal proliferation of plasma cells. These diseases include monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, multiple...

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TEMPI syndrome

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erythrocytosis, monoclonal gammopathy, perinephric fluid collection, and intrapulmonary shunting. The patients were all diagnosed at middle age. A monoclonal gammopathy...

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Plasma cell

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producing an antibody, which can be detected as a paraprotein. Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia characterized...

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Light chain deposition disease

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includes multiple myeloma, Waldenström's macroglobulinemia, and the monoclonal gammopathy of undetermined significance premalignant stages of these two diseases...

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Peripheral neuropathy

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electric shock, HIV, malignant disease, radiation, shingles, MGUS (Monoclonal gammopathy of undetermined significance). Peripheral neuropathy may first be...

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Irene Ghobrial

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multiple myeloma. She is interested in why certain patients with monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma...

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Dyscrasia

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dyscrasia" is sometimes considered synonymous with paraproteinemia or monoclonal gammopathy. H2 receptor antagonists, such as famotidine and nizatidine, in...

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Fanconi syndrome

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Lead poisoning also leads to Fanconi syndrome. Multiple myeloma or monoclonal gammopathy of undetermined significance can also cause the condition. Additionally...

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MGUS polyneuropathy

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characterized by inflammation of the peripheral nervous system and monoclonal gammopathy of undetermined significance (MGUS). It was first described in the...

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Hypercholesterolemia

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levels including diabetes mellitus type 2, obesity, alcohol use, monoclonal gammopathy, dialysis therapy, nephrotic syndrome, hypothyroidism, Cushing's...

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Schnitzler syndrome

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Blood tests show a high concentration of specific gamma-globulins (monoclonal gammopathy) of the IgM type. It almost always has light chains of the κ-type...

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Cryoglobulinemia

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this cancer, non-IgM monoclonal gammopathy of undetermined significance and non-IgM smoldering multiple myeloma. Non-IgM monoclonal immunoglobulin-based...

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