Excess myeloma protein or monoclonal gamma globulin in the blood
Medical condition
Monoclonal gammopathy
Other names
paraproteinemia
Serum protein electrophoresis shows gamma spike, or peak
Specialty
Oncology
Monoclonal gammopathy, also known as paraproteinemia, is the presence of excessive amounts of myeloma protein or monoclonal gamma globulin in the blood. It is usually due to an underlying immunoproliferative disorder or hematologic neoplasms, especially multiple myeloma. It is sometimes considered equivalent to plasma cell dyscrasia. The most common form of the disease is monoclonal gammopathy of undetermined significance.
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Monoclonalgammopathy, also known as paraproteinemia, is the presence of excessive amounts of myeloma protein or monoclonal gamma globulin in the blood...
Monoclonalgammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia in which plasma cells or other types of antibody-producing cells...
Monoclonalgammopathy of renal significance (MGRS) are a group of kidney disorders that present with kidney damage due to nephrotoxic monoclonal immunoglobulins...
fibre sensory modalities. Plasma cell dyscrasias are a group of monoclonalgammopathies in which normal plasma cells in the bone marrow and soft tissues...
proliferative diseases) are a spectrum of progressively more severe monoclonalgammopathies in which a clone or multiple clones of pre-malignant or malignant...
produced in excess by an abnormal monoclonal proliferation of plasma cells, typically in multiple myeloma or Monoclonalgammopathy of undetermined significance...
electrophoresis test are to diagnose or monitor multiple myeloma, a monoclonalgammopathy of uncertain significance (MGUS), or further investigate a discrepancy...
causation of multiple myeloma. Multiple myeloma may develop from monoclonalgammopathy of undetermined significance (MGUS) that progresses to smoldering...
hypogammaglobulinemia. A disease of gamma globulins is called a "gammopathy" (for example, in monoclonalgammopathy of undetermined significance). Brutton's agammaglobulinemia...
include certain colon polyps, which can progress into colon cancer, monoclonalgammopathy of undetermined significance, which can progress into multiple myeloma...
secreting monoclonal paraprotein (also termed myeloma protein or M protein) causes the relatively benign disease of monoclonalgammopathy of undetermined...
August 2022). "Management of Acute Episodes of Clarkson Disease (MonoclonalGammopathy-Associated Systemic Capillary Leak Syndrome) With Intravenous Immunoglobulins"...
polyneuropathy (CIDP) with subtypes: Classical CIDP CIDP with diabetes CIDP/monoclonalgammopathy of undetermined significance Sensory CIDP Multifocal motor neuropathy...
abnormal proliferation of plasma cells. These diseases include monoclonalgammopathy of undetermined significance, smoldering multiple myeloma, multiple...
erythrocytosis, monoclonalgammopathy, perinephric fluid collection, and intrapulmonary shunting. The patients were all diagnosed at middle age. A monoclonal gammopathy...
producing an antibody, which can be detected as a paraprotein. Monoclonalgammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia characterized...
includes multiple myeloma, Waldenström's macroglobulinemia, and the monoclonalgammopathy of undetermined significance premalignant stages of these two diseases...
electric shock, HIV, malignant disease, radiation, shingles, MGUS (Monoclonalgammopathy of undetermined significance). Peripheral neuropathy may first be...
multiple myeloma. She is interested in why certain patients with monoclonalgammopathy of undetermined significance (MGUS) and smoldering multiple myeloma...
dyscrasia" is sometimes considered synonymous with paraproteinemia or monoclonalgammopathy. H2 receptor antagonists, such as famotidine and nizatidine, in...
Lead poisoning also leads to Fanconi syndrome. Multiple myeloma or monoclonalgammopathy of undetermined significance can also cause the condition. Additionally...
characterized by inflammation of the peripheral nervous system and monoclonalgammopathy of undetermined significance (MGUS). It was first described in the...
Blood tests show a high concentration of specific gamma-globulins (monoclonalgammopathy) of the IgM type. It almost always has light chains of the κ-type...
this cancer, non-IgM monoclonalgammopathy of undetermined significance and non-IgM smoldering multiple myeloma. Non-IgM monoclonal immunoglobulin-based...