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Pyoderma gangrenosum information


Pyoderma gangrenosum
Pyoderma gangrenosum on the leg of a person with ulcerative colitis.
SpecialtyDermatology Edit this on Wikidata
Usual onset40s or 50s[1]
TreatmentCorticosteroids, ciclosporin, infliximab, canakinumab[2]

Pyoderma gangrenosum is a rare, inflammatory skin disease where painful pustules or nodules become ulcers that progressively grow.[3] Pyoderma gangrenosum is not infectious.[3]

Treatments may include corticosteroids, ciclosporin, infliximab, or canakinumab.[2]

The disease was identified in 1930. It affects approximately 1 person in 100,000 in the population. Though it can affect people of any age, it mostly affects people in their 40s and 50s.[1]

  1. ^ a b Jackson JM, Callen JP (April 23, 2012). Elston DM (ed.). "Pyoderma Gangrenosum". EMedicine.
  2. ^ a b Partridge AC, Bai JW, Rosen CF, Walsh SR, Gulliver WP, Fleming P (August 2018). "Effectiveness of systemic treatments for pyoderma gangrenosum: a systematic review of observational studies and clinical trials". The British Journal of Dermatology. 179 (2): 290–295. doi:10.1111/bjd.16485. PMID 29478243. S2CID 3504429.
  3. ^ a b Ruocco E, Sangiuliano S, Gravina AG, Miranda A, Nicoletti G (September 2009). "Pyoderma gangrenosum: an updated review". Journal of the European Academy of Dermatology and Venereology. 23 (9): 1008–17. doi:10.1111/j.1468-3083.2009.03199.x. PMID 19470075. S2CID 29773727.

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