POEMS syndrome (also termed osteosclerotic myeloma, Crow–Fukase syndrome, Takatsuki disease, or PEP syndrome) is a rare paraneoplastic syndrome caused by a clone of aberrant plasma cells. The name POEMS is an acronym for some of the disease's major signs and symptoms (polyneuropathy, organomegaly, endocrinopathy, myeloma protein, and skin changes), as is PEP (polyneuropathy, endocrinopathy, plasma cell dyscrasia).
The signs and symptoms of most neoplasms are due to their mass effects caused by the invasion and destruction of tissues by the neoplasms' cells. Signs and symptoms of a cancer causing a paraneoplastic syndrome result from the release of humoral factors such as hormones, cytokines, or immunoglobulins by the syndrome's neoplastic cells and/or the response of the immune system to the neoplasm. Many of the signs and symptoms in POEMS syndrome are due at least in part to the release of an aberrant immunoglobulin, i.e. a myeloma protein, as well as certain cytokines by the malignant plasma cells.[9][3][4]
POEMS syndrome typically begins in middle age – the average age at onset is 50 – and affects up to twice as many men as women.
^ abcd"POEMS syndrome — About the Disease — Genetic and Rare Diseases Information Center". rarediseases.info.nih.gov. Retrieved 2023-08-14.
^Cite error: The named reference pmid21035860 was invoked but never defined (see the help page).
^ abcdefWarsame R, Yanamandra U, Kapoor P (2017). "POEMS Syndrome: an Enigma". Current Hematologic Malignancy Reports. 12 (2): 85–95. doi:10.1007/s11899-017-0367-0. PMID 28299525. S2CID 31324035.
^ abcdefCite error: The named reference ajh was invoked but never defined (see the help page).
^ abNozza, Andrea (1 September 2017). "Poems Syndrome: An Update". Mediterranean Journal of Hematology and Infectious Diseases. 9 (1): e2017051. doi:10.4084/mjhid.2017.051. ISSN 2035-3006. PMC 5584767. PMID 28894560.
POEMSsyndrome (also termed osteosclerotic myeloma, Crow–Fukase syndrome, Takatsuki disease, or PEP syndrome) is a rare paraneoplastic syndrome caused...
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in San Rafael, California on November 11, 2019 at the age of 79 from POEMSsyndrome. 1964: "New Folks Volume 2" (Vanguard) 1965: "I like it this way" (Vanguard)...
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over half of surviving death poems (Ogiu, 317–318). Poetry has long been a core part of Japanese tradition. Death poems are typically graceful, natural...
those battling cancer and widening awareness of a rare illness called POEMSSyndrome". Chad also composed and performed the music for the short film The...
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90, American physicist. Lisa Kindred, 79, American folk musician, POEMSsyndrome. Winston Lackin, 64, Surinamese politician, Minister of Foreign Affairs...
praised her work in a poem of his own. Wheatley was emancipated by the Wheatleys shortly after the publication of her book of poems. The Wheatleys died...
has remained at an adolescent level, which is also known as "Peter Pan syndrome", a more recent pop-psychology label. In Jung's conception, the puer typically...
hypnosis Neuroplasticity Tetromino Video game addiction Phantom vibration syndrome Derealization Goldsmith, Jeffrey. "This Is Your Brain on Tetris". Wired...
Flower Eye of Venus Tim Lander 1938 poet Street Heart Poems Patrick Lane 1939 2019 poet Poems, New and Selected André Langevin 1927 2009 novelist, playwright...
member of the North Carolina House of Representatives (2003–2005), POEMSsyndrome. Tom Hendry, 83, Canadian playwright, founder of Manitoba Theatre Centre...
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