Spontaneously occurring or inherited disorder that involves mitochondrial dysfunction
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Medical condition
Mitochondrial disease
Other names
Mitochondrial cytopathy; mitochondriopathy (MCP)
Micrograph showing ragged red fibers, a finding seen in various types of mitochondrial diseases. Muscle biopsy. Gomori trichrome stain.
Specialty
Medical genetics
Mitochondrial disease is a group of disorders caused by mitochondrial dysfunction. Mitochondria are the organelles that generate energy for the cell and are found in every cell of the human body except red blood cells. They convert the energy of food molecules into the ATP that powers most cell functions.
Mitochondrial diseases take on unique characteristics both because of the way the diseases are often inherited and because mitochondria are so critical to cell function. A subclass of these diseases that have neuromuscular symptoms are known as mitochondrial myopathies.
and 27 Related for: Mitochondrial disease information
Mitochondrialdisease is a group of disorders caused by mitochondrial dysfunction. Mitochondria are the organelles that generate energy for the cell and...
been implicated in several human disorders and conditions, such as mitochondrialdiseases, cardiac dysfunction, heart failure and autism. The number of mitochondria...
Mitochondrial DNA depletion syndrome (MDS or MDDS), or Alper's disease, is any of a group of autosomal recessive disorders that cause a significant drop...
sustaining life. The mitochondrialdiseases are genetic disorders carried in mitochondrial DNA, or nuclear DNA coding for mitochondrial components. Slight...
haplogroup Human mitochondrial genetics MitochondrialdiseaseMitochondrial DNA (journal) Mitochondrial Eve Mitochondrial rCRS Paternal mtDNA transmission Single...
Mitochondrial myopathies are types of myopathies associated with mitochondrialdisease. Adenosine triphosphate (ATP), the chemical used to provide energy...
Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) is one of the family of mitochondrialdiseases, which also include MIDD...
variety of symbolic meanings. Mitochondrialdisease awareness is represented by a green ribbon. Mitochondrialdisease (mito) is a debilitating genetic...
Mutations in mitochondrial DNA (mtDNA) and over 30 genes in nuclear DNA (gene SURF1 and some COX assembly factors) have been implicated in Leigh disease. Disorders...
or ameliorate disease. MRT originated as a special form of in vitro fertilisation in which some or all of the future baby's mitochondrial DNA (mtDNA) comes...
encephalopathy, also called mad cow disease. The greatest risk factor for neurodegenerative diseases is aging. Mitochondrial DNA mutations as well as oxidative...
Environmental disease Host–pathogen interaction Lists of diseasesMitochondrialdisease Philosophy of medicine Plant pathology Rare disease, a disease that affects...
is MitochondrialDisease?". United MitochondrialDisease Foundation (UMDF). 14 January 2016. Saneto RP (2017). Genetics of MitochondrialDisease. Advances...
genome (mitochondrial DNA or plastid DNA) within a cell or individual. It is an important factor in considering the severity of mitochondrialdiseases. Because...
MERRF syndrome (or myoclonic epilepsy with ragged red fibers) is a mitochondrialdisease. It is extremely rare, and has varying degrees of expressivity owing...
Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or Lou Gehrig's disease in the United States, is a rare but terminal neurodegenerative...
Mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE) is a rare autosomal recessive mitochondrialdisease. It has been previously referred...
pressure support mode in a patient with autonomic dysfunction and mitochondrialdisease". Journal of Clinical Sleep Medicine. 17 (4): 853–857. doi:10.5664/jcsm...
of mitochondrial function Kearns–Sayre syndrome Disorders of peroxisomal function Zellweger syndrome Lysosomal storage disorders Gaucher's disease Niemann–Pick...
Pearson syndrome is a mitochondrialdisease characterized by sideroblastic anemia and exocrine pancreas dysfunction. Other clinical features are failure...
iron accumulation disorders, Wilson's disease, benign hereditary chorea, Friedreich's ataxia, mitochondrialdisease and Rett syndrome. The most common acquired...
immobilization. Creatine's impact on mitochondrial function has led to research on its efficacy and safety for slowing Parkinson's disease. As of 2014, the evidence...
neuropathy. It is important to stress that the vast majority of mitochondrialdiseases (particularly when symptoms develop in early life) are actually...
part, due to the unclear distinction between mitochondrialdisease and dysfunction. Mitochondrialdiseases are difficult to diagnose and have become better...
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