Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Methyl isocyanate (MIC) is an organic compound with the molecular formula CH3NCO. Synonyms are isocyanatomethane and methyl carbylamine. Methyl isocyanate is an intermediate chemical in the production of carbamate pesticides (such as carbaryl, carbofuran, methomyl, and aldicarb). It has also been used in the production of rubbers and adhesives. As an extremely toxic and irritating compound, it is very hazardous to human health. MIC was the principal toxicant involved in the Bhopal gas disaster, which eventually killed around 20,000 people in total as per official figures.[6][7][8][9][10][11][12] It is also a very potent lachrymatory agent.
^ abcdeNIOSH Pocket Guide to Chemical Hazards. "#0423". National Institute for Occupational Safety and Health (NIOSH).
^ abcdLide, David R., ed. (2006). CRC Handbook of Chemistry and Physics (87th ed.). Boca Raton, FL: CRC Press. ISBN 0-8493-0487-3.
^Lemoult (1898). Comptes Rendus Hebdomadaires des Séances de l'Académie des Sciences. 126: 43. {{cite journal}}: Missing or empty |title= (help)
^ ab"Methyl isocyanate". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
^"NFPA Hazard Rating Information for Common Chemicals". nmsu.edu. Archived from the original on 17 February 2015. Retrieved 10 June 2021.
^Methyl Isocyanate. Union Carbide F-41443A – 7/76. Union Carbide Corporation, New York 1976
^Operating Manual Part II. Methyl Isocyanate Unit. Union Carbide India Limited, Agricultural Products Division, 1979
^Broughton E (May 2005). "The Bhopal disaster and its aftermath: a review". Environmental Health. 4 (1): 6. Bibcode:2005EnvHe...4....6B. doi:10.1186/1476-069X-4-6. PMC 1142333. PMID 15882472.
^Eckerman I (2001). "Chemical Industry and Public Health — Bhopal as an example" (PDF). MPH. 2001 (24). Göteborg, Sweden: Nordic School of Public Health. ISSN 1104-5701. Archived (PDF) from the original on 30 October 2012.
^Eckerman I (2004). The Bhopal Saga - Causes and Consequences of the World's Largest Industrial Disaster. India: Universities Press. ISBN 81-7371-515-7. Archived from the original on 10 June 2007.
^Rosenberg J. "At 1984 - Huge Poison Gas Leak in Bhopal, India". About.com. Archived from the original on 2 December 2007. Retrieved 10 July 2008.
^Eckerman I (2013). "Bhopal Gas Catastrophe 1984: Causes and Consequences". Reference Module in Earth Systems and Environmental Sciences. Elsevier. pp. 272–287. doi:10.1016/B978-0-12-409548-9.01903-5. ISBN 978-0-12-409548-9.
Methylisocyanate (MIC) is an organic compound with the molecular formula CH3NCO. Synonyms are isocyanatomethane and methyl carbylamine. Methyl isocyanate...
chemistry, isocyanate is the functional group with the formula R−N=C=O. Organic compounds that contain an isocyanate group are referred to as isocyanates. An...
small towns around the plant were exposed to the highly toxic gas methylisocyanate (MIC). Estimates vary on the death toll, with the official number...
chemical in order to react with methylisocyanate and alpha naphthol. In 1970, there was an issue with the methylisocyanate unit being built (MIC) in Bhopal...
first prepared in 1849 by Charles-Adolphe Wurtz via the hydrolysis of methylisocyanate and related compounds. An example of this process includes the use...
containing bleach, causing the irritant gas monochloramine to be released. Methylisocyanate is an intermediate chemical in the production of carbamate pesticides...
In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula...
Methanol (also called methyl alcohol and wood spirit, amongst other names) is an organic chemical compound and the simplest aliphatic alcohol, with the...
used to produce monoisocyanates, used as pesticide precursors (e.g. methylisocyanate (MIC). Aside from the widely used reactions described above, phosgene...
Chemical Company) leaked a mixture of deadly gases composed mainly of methylisocyanate, leading to the worst industrial disaster in history. The Bhopal disaster...
Methanethiol /ˌmɛθ.eɪn.ˈθaɪ.ɒl/ (also known as methyl mercaptan) is an organosulfur compound with the chemical formula CH 3SH. It is a colorless gas with...
Methyl acetate, also known as MeOAc, acetic acid methyl ester or methyl ethanoate, is a carboxylate ester with the formula CH3COOCH3. It is a flammable...
(INN). Carbaryl is often inexpensively produced by direct reaction of methylisocyanate with 1-naphthol. C10H7OH + CH3NCO → C10H7OC(O)NHCH3 Alternatively...
seen for the first time on a comet, including acetamide, acetone, methylisocyanate and propionaldehyde. With an LD50 of 1690 mg/kg (oral), propionaldehyde...
seen for the first time on a comet, including acetamide, acetone, methylisocyanate, and propionaldehyde. The Merck Index, 15th Ed. (2013), p. 13, Acetone...
Acetonitrile, often abbreviated MeCN (methyl cyanide), is the chemical compound with the formula CH3CN and structure H3C−C≡N. This colourless liquid is...
revealed sixteen organic compounds, four of which – acetamide, acetone, methylisocyanate, and propionaldehyde – were seen for the first time on a comet. In...
instruments and untrained workers at the plant, a highly toxic gas Methylisocyanate (MIC) leaks into the atmosphere, instantly killing many workers, including...
Methyl radical is an organic compound with the chemical formula CH• 3 (also written as [CH 3]•). It is a metastable colourless gas, which is mainly produced...
and p-Toluenesulfonyl chloride have been used as a dehydrating agents. Isocyanates can be converted to carbodiimides with loss of carbon dioxide: 2 RN=C=O...
Coalition led by Andrew Peacock. December 3 – Bhopal disaster: A methylisocyanate leak from a Union Carbide pesticide plant in Bhopal, Madhya Pradesh...
Methyl isocyanide or isocyanomethane is an organic compound and a member of the isocyanide family. This colorless liquid is isomeric and isoelectronic...
catalyst, such as platinum, platinum-palladium, or iodine with sulfolane. 2-methyl-1,3-dioxolane is formed as a side product in the last case. Liquid ethylene...
group linked to a hydroxyl group), which indicates that the carbon of a methyl group (CH3−) is attached to the carbon of a methylene group (−CH2–), which...
exposure could cause death or major residual injury (e.g. aluminum phosphide, hydrogen cyanide, phosgene, diborane, methylisocyanate, hydrofluoric acid)...
In organic chemistry, methenium (also called methylium, carbenium, methyl cation, or protonated methylene) is a cation with the formula CH+ 3. It can be...
resulting in the formation of a hydrogen halide molecule and a methyl radical (•CH3). The methyl radical then reacts with a molecule of the halogen to form...
S2CID 119189492. Halfen, D. T.; et al. (2015), "Interstellar Detection of MethylIsocyanate CH3NCO in Sgr B2(N): A Link from Molecular Clouds to Comets", Astrophysical...
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