ethanol 500 g L−1[2] pyridine 166.67 g L−1[2] soluble in chloroform, glycerol, benzene[2]
log P
−1.26
Vapor pressure
1.3 Pa
Acidity (pKa)
15.1 (25 °C, H2O)[3]
Magnetic susceptibility (χ)
−0.577 × 10−6 cm3 g−1
Refractive index (nD)
1.4274
Viscosity
2.052 cP (91 °C)
Structure
Crystal structure
trigonal
Thermochemistry[4]
Heat capacity (C)
91.3 J·mol−1·K−1
Std molar entropy (S⦵298)
115.0 J·mol−1·K−1
Std enthalpy of formation (ΔfH⦵298)
−317.0 kJ·mol−1
Hazards
GHS labelling:
Pictograms
Signal word
Warning
Hazard statements
H351
Precautionary statements
P201, P202, P281, P308+P313, P405, P501
NFPA 704 (fire diamond)
3
1
1
Flash point
126 °C (259 °F; 399 K)
Lethal dose or concentration (LD, LC):
LD50 (median dose)
7000 mg kg−1 (rat, oral)
Safety data sheet (SDS)
External MSDS
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Chemical compound
Acetamide (systematic name: ethanamide) is an organic compound with the formula CH3CONH2. It is derived from acetic acid. It finds some use as a plasticizer and as an industrial solvent.[5] The related compound N,N-dimethylacetamide (DMA) is more widely used, but it is not prepared from acetamide. Acetamide can be considered an intermediate between acetone, which has two methyl (CH3) groups either side of the carbonyl (CO), and urea which has two amide (NH2) groups in those locations. Acetamide is also a naturally occurring mineral[6] with the IMA symbol: Ace.[7]
^"Front Matter". Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 841. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4.
^ abcdThe Merck Index, 14th Edition, 36
^Haynes, William M., ed. (2016). CRC Handbook of Chemistry and Physics (97th ed.). CRC Press. pp. 5–88. ISBN 9781498754293.
^John Rumble (June 18, 2018). CRC Handbook of Chemistry and Physics (99th ed.). CRC Press. pp. 5–3. ISBN 978-1138561632.
^Cite error: The named reference ullmann was invoked but never defined (see the help page).
Acetamide (systematic name: ethanamide) is an organic compound with the formula CH3CONH2. It is derived from acetic acid. It finds some use as a plasticizer...
National Institute for Occupational Safety and Health (NIOSH). "Dimethyl acetamide". Immediately Dangerous to Life or Health Concentrations (IDLH). National...
joined to an amine group. Common of amides are formamide (H−C(=O)−NH2), acetamide (H3C−C(=O)−NH2), benzamide (C6H5−C(=O)−NH2), and dimethylformamide (H−C(=O)−N(−CH3)2)...
Phenacetin (acetophenetidin, N-(4-ethoxyphenyl)acetamide) is a pain-relieving and fever-reducing drug, which was widely used following its introduction...
after R. Minderer, a physician from Augsburg. It is the main precursor to acetamide: NH4CH3CO2 → CH3C(O)NH2 + H2O It is also used as a diuretic. As the salt...
as in intermediate in the production of some dyes. "N-(4-Nitrophenyl)acetamide (compound)". Retrieved 5 December 2021. "Dyes and Dye Intermediates" in...
2-amino-N-(2-benzoyl-4-bromophenyl)acetamide. Upon the formation of 2-amino-N-(2-benzoyl-4-bromophenyl)acetamide, an intramolecular reaction ensues,...
Generally a base is employed to absorb the HCl coproduct. Bis(trimethylsilyl)acetamide ("BSA", Me3SiNC(OSiMe3)Me is an efficient silylation agent. The reaction...
mass: 59.07 g/mol, exact mass: 59.03711 u) may refer to: Acetaldoxime Acetamide Aminoacetaldehyde N-Methylformamide (NMF) This set index page lists chemical...
are aluminium acetate, used in dyeing, ammonium acetate, a precursor to acetamide, and potassium acetate, used as a diuretic. All three salts are colourless...
trimethylsilylating agents include trimethylsilyl chloride and bis(trimethylsilyl)acetamide. Trimethylsilyl groups on a molecule have a tendency to make it more volatile...
They are sorted by the partition coefficient, smallest to largest (acetamide being hydrophilic, and 2,2',4,4',5-pentachlorobiphenyl lipophilic), and...
compounds, four of which were seen for the first time on a comet, including acetamide, acetone, methyl isocyanate and propionaldehyde. With an LD50 of 1690...
least sixteen organic compounds at the comet's surface, four of which (acetamide, acetone, methyl isocyanate and propionaldehyde) have been detected for...
includes the use of the Hofmann rearrangement, to yield methylamine from acetamide and bromine. In the laboratory, methylamine hydrochloride is readily prepared...
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