Mepolizumab, sold under the brand name Nucala by GlaxoSmithKline, is a humanized monoclonal antibody used for the treatment of severe eosinophilic asthma, eosinophilic granulomatosis, and hypereosinophilic syndrome (HES).[5] It recognizes and blocks interleukin-5 (IL-5), a signalling protein of the immune system.
The most common side effects include headache, injection site reactions, and back pain.[4]
^"Mepolizumab (Nucala) Use During Pregnancy". Drugs.com. 14 June 2019. Retrieved 8 October 2020.
^"Prescription medicines: registration of new chemical entities in Australia, 2016". Therapeutic Goods Administration (TGA). 21 June 2022. Retrieved 10 April 2023.
^"Health Canada New Drug Authorizations: 2015 Highlights". Health Canada. 4 May 2016. Retrieved 7 April 2024.
^ abCite error: The named reference Nucala EPAR was invoked but never defined (see the help page).
^Cite error: The named reference FDA PR 20200925 was invoked but never defined (see the help page).
Mepolizumab, sold under the brand name Nucala by GlaxoSmithKline, is a humanized monoclonal antibody used for the treatment of severe eosinophilic asthma...
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