This article is about the disease. For the philosophical use, see Atopy (philosophy).
Medical condition
Atopy
Other names
Atopic syndrome
Eczema—a typical atopic manifestation
Pronunciation
/ˈætəpiː/[1]
Specialty
Dermatology, immunology
Atopy is the tendency to produce an exaggerated immunoglobulin E (IgE) immune response to otherwise harmless substances in the environment.[2] Allergic diseases are clinical manifestations of such inappropriate, atopic responses.[2]
Atopy may have a hereditary component, although contact with the allergen or irritant must occur before the hypersensitivity reaction can develop (characteristically after re-exposure).[3] Maternal psychological trauma in utero may also be a strong indicator for development of atopy.[4]
The term atopy was coined by Arthur F. Coca and Robert Cooke in 1923.[5][6] Many physicians and scientists use the term "atopy" for any IgE-mediated reaction (even those that are appropriate and proportional to the antigen), but many pediatricians reserve the word "atopy" for a genetically mediated predisposition to an excessive IgE reaction.[7] The term is from Greek ἀτοπία meaning "the state of being out of place", "absurdity".[8]
^Merriam-Webster Dictionary: Atopy
^ abRalston, Stuart H., Herausgeber. Penman, Ian D., Herausgeber. Strachan, Mark W. J., Herausgeber. Hobson, Richard P., Herausgeber. Britton, Robert, Illustrator. Davidson, Leybourne S. 1894-1981 Begründer des Werks. (2018-04-23). Davidson's principles and practice of medicine. Elsevier. ISBN 978-0-7020-7028-0. OCLC 1040673074.{{cite book}}: CS1 maint: multiple names: authors list (link) CS1 maint: numeric names: authors list (link)
^"Mosby's Medical Dictionary:atopy". Archived from the original on 2011-07-10.
^Wright, Rosalind J; Enlow, Michelle Bosquet (2008-09-01). "Maternal stress and perinatal programming in the expression of atopy". Expert Review of Clinical Immunology. 4 (5): 535–538. doi:10.1586/1744666X.4.5.535. ISSN 1744-666X. PMC 2762209. PMID 19838310.
^Coca AF, Cooke RA. (1923) On the classification of the phenomenon of hypersensitiveness J Immunol
^Johannes Ring; Bernhard Przybilla; Thomas Ruzicka (2006). Handbook of atopic eczema. Birkhäuser. pp. 3–. ISBN 978-3-540-23133-2. Retrieved 4 May 2010.
^Ruby Pawankar; Stephen T. Holgate; Lanny J. Rosenwasser (7 April 2009). Allergy Frontiers: Classification and Pathomechanisms. Springer. pp. 33–. ISBN 978-4-431-88314-2. Retrieved 4 May 2010.
Atopy is the tendency to produce an exaggerated immunoglobulin E (IgE) immune response to otherwise harmless substances in the environment. Allergic diseases...
expiratory flow rate. It may also be classified as atopic or non-atopic, where atopy refers to a predisposition toward developing a type 1 hypersensitivity reaction...
has been occurring since the 1920s. The number of new cases per year of atopy in developing countries has, in general, remained much lower. Although genetic...
inflammation and ulcers. It is most commonly seen in patients with a history of atopy, however is overall relatively uncommon. In Germany, 90% of cases of infectious...
celiac disease. Other more common symptoms include nausea, urticaria, and atopy. Gluten sensitivity and Coeliac disease are two different diseases even...
Luzzi GA, Bell R. Clinical features and management of recurrent balanitis: association with atopy and genital washing. Genitourin Med 1993;69(5):400-3....
JM (November 1994). "Abnormal skin irritancy in atopic dermatitis and in atopy without dermatitis". Archives of Dermatology. 130 (11): 1402–7. doi:10.1001/archderm...
the source of the allergen is usually sufficient in solving the problem. Atopy is synonymous with "inhalant allergy." It manifests as a condition called...
vasoactive biomolecules. Testing can be done via skin test for specific IgE. Atopy Anaphylaxis Asthma Churg–Strauss Syndrome II Antibody-dependent Antibody...
reading. Look up effable or ineffable in Wiktionary, the free dictionary. Atopy (philosophy) Apophatic (or "negative") theology Creator ineffabilis (Christian...
ranging from deafness to fatal flaws. Skin diseases are very common in dogs. Atopy, a chronic allergic condition, is thought to affect up to 10 percent of...
Surisan (Korean: 수리산) is a mountain separating the cities of Anyang and Gunpo in Gyeonggi Province, South Korea. Surisan is 488 metres (1,601 ft) above...
and of food offered at the venue. Concerns about the clothes increasing atopy symptoms in patients, or even of accidentally hosting parasites, have been...
December 2017. Feary, J.; Britton, J.; Leonardi-Bee, J. (April 2011). "Atopy and current intestinal parasite infection: a systematic review and meta-analysis"...
in adulthood. Symptoms include atopic dermatitis, food allergy, allergic rhinitis and asthma. Atopy The Allergic March Atopic March Definition v t e...
Cushing's syndrome, thyroid and autoimmune problems, various allergies and atopies, and various eye conditions including cataracts, glaucoma, progressive...
JM (November 1994). "Abnormal skin irritancy in atopic dermatitis and in atopy without dermatitis". Arch Dermatol. 130 (11): 1402–7. doi:10.1001/archderm...
study of 90,000 dog's patient records found coonhounds to be predisposed to atopy/allergic dermatitis with 8.33% of coonhounds having the condition compared...
Zhang Q, Shakya S, Li ZY (February 2016). "Probiotics for Prevention of Atopy and Food Hypersensitivity in Early Childhood: A PRISMA-Compliant Systematic...
aware of the scratching they do in their sleep. LSC is also associated with atopy, or atopic dermatitis (eczema) and an increase of histamine levels. LSC...
"Clinical features and management of recurrent balanitis: association with atopy and genital washing". Genitourin Med. 69 (5): 400–403. doi:10.1136/sti.69...
most important contact sensitizers in Polish children and adolescents with atopy and chronic recurrent eczema as detected with the extended European Baseline...
sex Having older siblings Maternal smoking during pregnancy History of atopy (tendency to develop allergic diseases) No breastfeeding Household crowding...
developing allergic diseases (defined as at least one parent or sibling having atopy), atopic syndrome can be prevented or delayed through 4-month exclusive...
fluoridated toothpaste and inhaled corticosteroids. A high prevalence of atopy has been found in those with perioral dermatitis. The possibility of an...
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