Mazindol information

Mazindol
Clinical data
Trade names	Mazanor, Sanorex
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Routes of; administration	Oral
ATC code	A08AA05 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only); BR: Class B2 (Anorectic drugs); CA: Schedule IV; DE: Anlage II (Authorized trade only, not prescriptible); US: Schedule IV; Schedule IV (International)[how?];
Pharmacokinetic data
Bioavailability	93%
Metabolism	Hepatic
Elimination half-life	10–13 hours
Excretion	Renal
Identifiers
	IUPAC name (±)-5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol;
CAS Number	22232-71-9 ;
PubChem CID	4020;
IUPHAR/BPS	4797;
DrugBank	DB00579 ;
ChemSpider	3880 ;
UNII	C56709M5NH;
KEGG	D00367 ;
ChEMBL	ChEMBL781 ;
CompTox Dashboard (EPA)	DTXSID1023237 ;
ECHA InfoCard	100.040.764
Chemical and physical data
Formula	C16H13ClN2O
Molar mass	284.74 g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES ClC1=CC=C(C2(C3=CC=CC=C3C4=NCCN42)O)C=C1;
	InChI InChI=1S/C16H13ClN2O/c17-12-7-5-11(6-8-12)16(20)14-4-2-1-3-13(14)15-18-9-10-19(15)16/h1-8,20H,9-10H2 ; Key:ZPXSCAKFGYXMGA-UHFFFAOYSA-N ;
	(verify)

Mazindol (brand names Mazanor, Sanorex) is a stimulant drug which is used as an appetite suppressant.^[2] It was developed by Sandoz-Wander in the 1960s.^[3]

^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
^ Carruba MO, Zambotti F, Vicentini L, Picotti GB, Mantegazza P (1978). "Pharmacology and biochemical profile of a new anorectic drug: mazindol". Cent. Mech. Anorectic Drugs: 145–64.
^ Cite error: The named reference US3597445 was invoked but never defined (see the help page).

[1] Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.

[2] Carruba MO, Zambotti F, Vicentini L, Picotti GB, Mantegazza P (1978). "Pharmacology and biochemical profile of a new anorectic drug: mazindol". Cent. Mech. Anorectic Drugs: 145–64.

[US3597445-3] Cite error: The named reference US3597445 was invoked but never defined (see the help page).

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C16H13ClN2O