Mast cell sarcoma is an extremely aggressive[2] form of sarcoma made up of neoplastic mast cells. A sarcoma is a tumor made of cells from connective tissue. Mast cell sarcoma is an extremely rare tumor. The largest analysis to date comprises 34 cases.[3] Prognosis is extremely poor. People with a mast cell sarcoma have no skin lesions, and pathology examination of the tumor shows it to be very malignant with an aggressive growth pattern.[4] Mast cell sarcoma should not be confused with
extracutaneous mastocytoma, a rare benign mast cell tumor without destructive growth. In the cases observed, mast cell sarcoma terminated quickly as mast cell leukemia; one of the most aggressive human cancers.[5]
^Chott A, Guenther P, Huebner A, Selzer E, Parwaresch R, Horny H, Valent P (2003). "Morphologic and immunophenotypic properties of neoplastic cells in a case of mast cell sarcoma". Am J Surg Pathol. 27 (7): 1013–9. doi:10.1097/00000478-200307000-00019. PMID 12826896. S2CID 46710032.
^Matsumoto, Nana P.; Yuan, Ji; Wang, Jun; Shen, Qi; Chen, Xueyan; Kim, Young; Zuppan, Craig W.; Chang, Chung-Che; Cui, Wei; Chen, Dong; Shi, Min; Gisriel, Savanah D.; Chen, Mingyi; Xu, Mina L.; Pan, Zenggang (July 2022). "Mast cell sarcoma: clinicopathologic and molecular analysis of 10 new cases and review of literature". Modern Pathology. 35 (7): 865–874. doi:10.1038/s41379-022-01014-w. PMID 35105959.
^Nancy Gould, "Diagnosis and Classification of Mastocytosis Archived 2004-10-27 at the Wayback Machine", The Mastocytosis Society.
^Ansell, Stephen M., ed. (2008). Rare Hematological Malignancies. doi:10.1007/978-0-387-73744-7. ISBN 978-0-387-73743-0.[page needed]
Mastcellsarcoma is an extremely aggressive form of sarcoma made up of neoplastic mastcells. A sarcoma is a tumor made of cells from connective tissue...
A mastcell (also known as a mastocyte or a labrocyte) is a resident cell of connective tissue that contains many granules rich in histamine and heparin...
cancer of the white blood cells. It is a form of leukemia characterized by the increased and unregulated growth of myeloid cells in the bone marrow and the...
blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production...
decreased production of blood cells such as erythrocytes (red cells), granulocytes and megakaryocytes, the latter cells responsible for the production...
A mastocytoma in dogs (or mastcell tumor in dogs) is a neoplasm (neoplasia) originating from mastcells in the domestic dog, which occurs mainly in the...
of systemic mastocytosis Another known but rare mastcell proliferation disease is mastcellsarcoma. Mastocytosis can occur in a variety of forms: The...
corticosteroids, argon and carbon dioxide lasers, and surgical excision. Mastcellsarcoma List of cutaneous conditions Rapini, Ronald P.; Bolognia, Jean L.;...
Sarcoma: Cancers arising from connective tissue (i.e. bone, cartilage, fat, nerve), each of which develop from cells originating in mesenchymal cells...
release of inflammatory mediators, including histamine from cutaneous mastcells, results in fluid leakage from superficial blood vessels. Hives may be...
cells of connective tissue include fibroblasts, adipocytes, macrophages, mastcells and leukocytes. The term "connective tissue" (in German, Bindegewebe)...
product/CD117 is expressed on ICCs and a large number of other cells, mainly bone marrow cells, mastcells, melanocytes and several others. In the gut, however...
those found in humans. Dogs can develop carcinomas of epithelial cells and organs, sarcomas of connective tissues and bones, and lymphomas or leukemias of...
test, also Tzanck smear, is scraping of an ulcer base to look for Tzanck cells. It is sometimes also called the chickenpox skin test and the herpes skin...
Y (October 2004). "T cell proliferation by direct cross-talk between OX40 ligand on human mastcells and OX40 on human T cells: comparison of gene expression...
bromides, and cyclosporine. A significant increase in the density of mastcells has been seen in cherry hemangiomas compared with normal skin. The diagnosis...
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