MTF1 information

MTF1
Identifiers
Aliases	MTF1, MTF-1, ZRF, metal-regulatory transcription factor 1, metal regulatory transcription factor 1
External IDs	OMIM: 600172; MGI: 101786; HomoloGene: 4347; GeneCards: MTF1; OMA:MTF1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	37,859,592 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	124,743,593 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; buccal mucosa cell; ; mucosa of paranasal sinus; ; oral cavity; ; epithelium of bronchus; ; bronchial epithelial cell; ; nipple; ; internal globus pallidus; ; tendon of biceps brachii; ; gums;
	Top expressed in
	spermatid; ; zygote; ; spermatocyte; ; seminiferous tubule; ; secondary oocyte; ; primary oocyte; ; internal carotid artery; ; motor neuron; ; lacrimal gland; ; retinal pigment epithelium;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; transcription coactivator activity; DNA-binding transcription activator activity, RNA polymerase II-specific; metal ion binding; protein binding; histone acetyltransferase binding; nucleic acid binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; cis-regulatory region sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding;
Cellular component	nucleus; nucleoplasm;
Biological process	response to cadmium ion; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; response to metal ion; response to oxidative stress; transcription, DNA-templated; positive regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; central nervous system development;
	Sources:Amigo / QuickGO
Orthologs
	4520
	17764
	ENSG00000188786
	ENSMUSG00000028890
	Q14872
	Q07243
	NM_005955
	NM_008636
	NP_005946
	NP_032662
	Wikidata
View/Edit Human	View/Edit Mouse

Metal regulatory transcription factor 1 is a protein that in humans is encoded by the MTF1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000188786 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028890 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Brugnera E, Georgiev O, Radtke F, Heuchel R, Baker E, Sutherland GR, Schaffner W (Aug 1994). "Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1". Nucleic Acids Research. 22 (15): 3167–73. doi:10.1093/nar/22.15.3167. PMC 310292. PMID 8065932.
^ "Entrez Gene: MTF1 metal-regulatory transcription factor 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000188786 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028890 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8065932-5] Brugnera E, Georgiev O, Radtke F, Heuchel R, Baker E, Sutherland GR, Schaffner W (Aug 1994). "Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1". Nucleic Acids Research. 22 (15): 3167–73. doi:10.1093/nar/22.15.3167. PMC 310292. PMID 8065932.

[entrez-6] "Entrez Gene: MTF1 metal-regulatory transcription factor 1".

MTF1 information

and 24 Related for: MTF1 information

MTF1

Specificity factor

List of human transcription factors

Homeobox

Zinc finger

P53

DMRT1

FOXP2

Transcription factor

Estrogen receptor

CREB

Androgen receptor

Hormone receptor

Retinoblastoma protein

Nuclear receptor

NBPF26

HIF1A

Sigma factor

Heterochromatin protein 1

Glucocorticoid receptor

FOSB

General transcription factor

NFE2L2

Transcription factor II D