NBPF26 information

NBPF26
Identifiers
Aliases	NBPF26, NBPF member 26
External IDs	HomoloGene: 41035; GeneCards: NBPF26; OMA:NBPF26 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	120,842,110 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; ventricular zone; ; Achilles tendon; ; right coronary artery; ; gastric mucosa; ; granulocyte; ; skin of leg; ; appendix; ; skin of abdomen; ; blood;
	n/a
	More reference expression data
	n/a
Orthologs
	101060684
	n/a
	ENSG00000273136
	n/a
	n; a
	n/a
	NM_001351372; NM_001395637; NM_001405520
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

NBPF26, or Neuroblastoma breakpoint family member 26, is a protein encoded by the NBPF26 gene in Homo sapiens. The alias for NBPF26 is notch 2 N-terminal like R (NOTCH2NLR).^[3] NBPF26 encodes 13 Olduvai domains, which are thought to contribute to the rapid expansion of the neocortex in humans.^[4]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000273136 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ NCBI gene entry for NBPF26
^ Fiddes, I. T., Pollen, A. A., Davis, J. M., & Sikela, J. M. (2019). Paired involvement of human-specific Olduvai domains and NOTCH2NL genes in human brain evolution. Human genetics, 138, 715-721.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000273136 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] NCBI gene entry for NBPF26

[4] Fiddes, I. T., Pollen, A. A., Davis, J. M., & Sikela, J. M. (2019). Paired involvement of human-specific Olduvai domains and NOTCH2NL genes in human brain evolution. Human genetics, 138, 715-721.

NBPF26 information

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Olduvai domain