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MRP2 information


MRP2 may refer to:

  • Multidrug resistance-associated protein 2
  • Manufacturing resource planning (MRP2 or MRP II)

and 23 Related for: MRP2 information

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MRP2

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MRP2 may refer to: Multidrug resistance-associated protein 2 Manufacturing resource planning (MRP2 or MRP II) This disambiguation page lists articles associated...

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Eluxadoline

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resistance-associated protein 2 (MRP2)-vesicular accumulation of eluxadoline was observed, indicating that the drug is a substrate of MRP2. Eluxadoline was not found...

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Bilirubin diglucuronide

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across the hepatic canalicular membrane into the bile by the transporter MRP2. Bilirubin mono-glucuronide Chowdhury, J. R.; Chowdhury, N. R.; Wu, G.; Shouval...

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Liver function tests

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Dubin–Johnson syndrome, a mutation in multiple drug-resistance protein 2 (MRP2) causes a rise in conjugated bilirubin. In acute appendicitis, total bilirubin...

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Manufacturing resource planning

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Manufacturing Resource Planning or Management resource planning (or MRP2) - Around 1980, over-frequent changes in sales forecasts, entailing continual...

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Hyperbilirubinemia in adults

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across the plasma membrane by multidrug resistant-associated protein 2 (MRP2) to finally enter bile capillaries. From there, conjugated bilirubin is secreted...

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Material requirements planning

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considered a true MRP II system must also include financials. In the MRP II (or MRP2) concept, fluctuations in forecast data are taken into account by including...

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Cholestasis

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for inhibition, MRP2 is an apical efflux transporter that mainly exports bilirubin glucuronide and glutathione into bile. However, MRP2 is also the preferential...

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Amiodarone

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amiodarone is transported into bile via multidrug-resistant protein 2 (MRP2) transporter. Bile containing amiodarone and its metabolites is then released...

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Ethinylestradiol

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jaundice. Glucuronide metabolites of EE, via effects on the ABCB11 (BSEP) and MRP2 (ABCC2) proteins and consequent changes in bile flow and bile salt excretion...

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Angiotensin II receptor blocker

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CYP2C9 Valsartan Diovan 6 2–4 hrs 95% 25% 30/70% Yes 80–320 Substrates: MRP2 and OATP1B1/SLCO1B1 Irbesartan Avapro 11–15 1.5–2 hrs 90–95% 70% 20/80% No...

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Drug metabolism

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resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance". Biochim. Biophys. Acta. 1461 (2): 377–94. doi:10...

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Bilirubin glucuronide

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12-diglucuronide) and be excreted into bile canaliculi by way of C-MOAT and MRP2 as normal human bile along with a little amount of unconjugated bilirubin...

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Estradiol glucuronide

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by OATP1A2, OATP1B1, OATP1B3, OATP1C1, and OATP3A1. The ABC transporters MRP2, MRP3, MRP4, and BCRP, as well as several other transporters, have been found...

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Abacavir

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decreased absorption of abacavir by orlistat. Cabozantinib: Drugs from the MRP2 inhibitor (Multidrug resistance-associated protein 2 inhibitors) family such...

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Cystic fibrosis transmembrane conductance regulator

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Bakos E, Váradi A, et al. (March 2003). "C-terminal phosphorylation of MRP2 modulates its interaction with PDZ proteins". Biochemical and Biophysical...

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Xenobiotic metabolism

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resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance". Biochim. Biophys. Acta. 1461 (2): 377–94. doi:10...

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Pharmacodynamics of spironolactone

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(multidrug resistance protein 1; MRP1; ABCB1) and multidrug resistance protein 2 (MRP2; ABCC2). These proteins are involved in the metabolism and elimination of...

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Bouvardia longiflora

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Bouvardia longiflora Wikidata: Q15399245 Wikispecies: Bouvardia longiflora CoL: MRP2 EoL: 1111356 EPPO: BVALO GBIF: 2910298 GRIN: 7536 iNaturalist: 286123 IPNI:...

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PDZK1

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up-regulated in carcinomas and mapped to chromosome 1q21, interacts with cMOAT (MRP2), the multidrug resistance-associated protein". Lab. Invest. 79 (9): 1161–70...

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ABCC3

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MJ, Juijn JA, Baas F, Borst P (1997). "Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated...

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Darolutamide

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shows no inhibition of a variety of other transporters (P-glycoprotein, MRP2, BSEP, OATs, OCTs, MATEs, OATP2B1, NTCP) at therapeutic concentrations. The...

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Var1 protein domain

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(May 1995). "Incorporation of the yeast mitochondrial ribosomal protein Mrp2 into ribosomal subunits requires the mitochondrially encoded Var1 protein"...

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