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Cholestasis information


Cholestasis
Micrograph showing bile (yellow) stasis in liver tissue, i.e. cholestasis. H&E stain.
SpecialtyGastroenterology

Cholestasis is a condition where the flow of bile from the liver to the duodenum is impaired.[1] The two basic distinctions are:[1]

  • obstructive type of cholestasis, where there is a mechanical blockage in the duct system that can occur from a gallstone or malignancy, and
  • metabolic type of cholestasis, in which there are disturbances in bile formation that can occur because of genetic defects or acquired as a side effect of many medications.

Classification is further divided into acute or chronic and extrahepatic or intrahepatic.

  1. ^ a b "Cholestasis: Background, Pathophysiology, Epidemiology". 2021-04-03. {{cite journal}}: Cite journal requires |journal= (help)

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