MAFK information

MAFK
Identifiers
Aliases	MAFK, NFE2U, P18, MAF bZIP transcription factor K
External IDs	OMIM: 600197 MGI: 99951 HomoloGene: 1770 GeneCards: MAFK
Gene location (Human)
Chr.	Chromosome 7 (human)
End	1,543,043 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	139,788,408 bp
RNA expression pattern
	Top expressed in
	ascending aorta; ; popliteal artery; ; right coronary artery; ; gastric mucosa; ; right lung; ; saphenous vein; ; left coronary artery; ; left ventricle; ; gastrocnemius muscle; ; upper lobe of left lung;
	Top expressed in
	ascending aorta; ; aortic valve; ; jejunum; ; yolk sac; ; digastric muscle; ; lip; ; right lung lobe; ; tibialis anterior muscle; ; crypt of lieberkuhn of small intestine; ; stomach;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; transcription coregulator binding; transcription cis-regulatory region binding; protein binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RING-like zinc finger domain binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific;
Cellular component	nucleoplasm; nucleus;
Biological process	blood coagulation; regulation of transcription, DNA-templated; nervous system development; transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7975
	17135
	ENSG00000198517
	ENSMUSG00000018143
	O60675
	Q61827
	NM_002360
	NM_010757
	NP_002351
	NP_034887
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor MafK is a bZip Maf transcription factor protein that in humans is encoded by the MAFK gene.^[5]^[6]

MafK is one of the small Maf proteins, which are basic region and leucine zipper (bZIP)-type transcription factors. The HUGO Gene Nomenclature Committee-approved gene name of MAFK is “v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K”.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000198517 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000018143 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Fujiwara KT, Kataoka K, Nishizawa M (Sep 1993). "Two new members of the maf oncogene family, mafK and mafF, encode nuclear b-Zip proteins lacking putative trans-activator domain". Oncogene. 8 (9): 2371–80. PMID 8361754.
^ "Entrez Gene: MAFK v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000198517 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000018143 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[Fujiwara_1993-5] Fujiwara KT, Kataoka K, Nishizawa M (Sep 1993). "Two new members of the maf oncogene family, mafK and mafF, encode nuclear b-Zip proteins lacking putative trans-activator domain". Oncogene. 8 (9): 2371–80. PMID 8361754.

[entrez-6] "Entrez Gene: MAFK v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)".

MAFK information

and 15 Related for: MAFK information

MAFK

Small Maf

List of human transcription factors

NFE2L2

MAFG

BACH1

BZIP domain

BACH2

JackEL discography

JackEL

Transactivation domain

Jun dimerization protein

Uncharacterized protein C15orf32

ZNF337

NFE2L1