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ZNF337 information


ZNF337
Identifiers
AliasesZNF337, zinc finger protein 337
External IDsHomoloGene: 49427 GeneCards: ZNF337
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001290261
NM_015655

n/a

RefSeq (protein)

NP_001277190
NP_056470

n/a

Location (UCSC)Chr 20: 25.67 – 25.7 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

ZNF337, also known as zinc finger protein 337, is a protein that in humans is encoded by the ZNF337 gene. The ZNF337 gene is located on human chromosome 20 (20p11.21). Its protein contains 751 amino acids, has a 4,237 base pair mRNA and contains 6 exons total.[3] In addition, alternative splicing results in multiple transcript variants.[4] The ZNF337 gene encodes a zinc finger domain containing protein, however, this gene/protein is not yet well understood by the scientific community. The function of this gene has been proposed to participate in a processes such as the regulation of transcription (DNA-dependent), and proteins are expected to have molecular functions such as DNA binding, metal ion binding, zinc ion binding, which would be further localized in various subcellular locations.[5][6] While there are no commonly associated or known aliases, an important paralog of this gene is ZNF875 [7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130684 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "ZNF337 zinc finger protein 337 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2020-04-29.
  4. ^ "Homo sapiens zinc finger protein 337 (ZNF337), transcript variant 2, mRNA". 2019-08-22. {{cite journal}}: Cite journal requires |journal= (help)
  5. ^ Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, et al. (20–27 December 2001). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
  6. ^ "AceView: Gene:ZNF337, a comprehensive annotation of human, mouse and worm genes with mRNAs or ESTsAceView". www.ncbi.nlm.nih.gov. Retrieved 2020-04-29.
  7. ^ "ZNF337 Gene - GeneCards | ZN337 Protein | ZN337 Antibody". www.genecards.org. Retrieved 2020-04-29.

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ZNF337

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ZNF337, also known as zinc finger protein 337, is a protein that in humans is encoded by the ZNF337 gene. The ZNF337 gene is located on human chromosome...

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List of human transcription factors

Last Update:

specific TF according to literature or domain structure – No motif [1,245] ZNF337 ENSG00000130684 C2H2 ZF Known motif – High-throughput in vitro [1,246] AGTRGTGAYRAATTC...

Word Count : 81

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