ZNF337, also known as zinc finger protein 337, is a protein that in humans is encoded by the ZNF337 gene. The ZNF337 gene is located on human chromosome 20 (20p11.21). Its protein contains 751 amino acids, has a 4,237 base pair mRNA and contains 6 exons total.[3] In addition, alternative splicing results in multiple transcript variants.[4] The ZNF337 gene encodes a zinc finger domain containing protein, however, this gene/protein is not yet well understood by the scientific community. The function of this gene has been proposed to participate in a processes such as the regulation of transcription (DNA-dependent), and proteins are expected to have molecular functions such as DNA binding, metal ion binding, zinc ion binding, which would be further localized in various subcellular locations.[5][6] While there are no commonly associated or known aliases, an important paralog of this gene is ZNF875 [7]
^ abcGRCh38: Ensembl release 89: ENSG00000130684 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, et al. (20–27 December 2001). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
^"AceView: Gene:ZNF337, a comprehensive annotation of human, mouse and worm genes with mRNAs or ESTsAceView". www.ncbi.nlm.nih.gov. Retrieved 2020-04-29.
ZNF337, also known as zinc finger protein 337, is a protein that in humans is encoded by the ZNF337 gene. The ZNF337 gene is located on human chromosome...
specific TF according to literature or domain structure – No motif [1,245] ZNF337 ENSG00000130684 C2H2 ZF Known motif – High-throughput in vitro [1,246] AGTRGTGAYRAATTC...