MAFG information

MAFG
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1K1V, 3A5T
Identifiers
Aliases	MAFG, hMAF, MAF bZIP transcription factor G
External IDs	OMIM: 602020 MGI: 96911 HomoloGene: 81816 GeneCards: MAFG
Gene location (Human)
Chr.	Chromosome 17 (human)
End	81,927,735 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	120,524,426 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; amniotic fluid; ; nipple; ; ventral tegmental area; ; middle temporal gyrus; ; pons; ; superior vestibular nucleus; ; body of tongue; ; Brodmann area 23; ; vena cava;
	Top expressed in
	lens; ; lip; ; yolk sac; ; superior frontal gyrus; ; saccule; ; ectoderm; ; otic placode; ; left lobe of liver; ; knee joint; ; dorsomedial hypothalamic nucleus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; protein binding; protein heterodimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding;
Cellular component	nucleoplasm; nucleus;
Biological process	regulation of epidermal cell differentiation; positive regulation of gene expression; adult behavior; blood coagulation; in utero embryonic development; regulation of cell population proliferation; regulation of cellular pH; regulation of transcription, DNA-templated; transcription, DNA-templated; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	4097
	17134
	ENSG00000197063
	ENSMUSG00000051510
	O15525
	O54790
	NM_002359; NM_032711
	NM_010756
	NP_002350; NP_116100
	NP_034886
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor MafG is a bZip Maf transcription factor protein that in humans is encoded by the MAFG gene.^[5]^[6]

MafG is one of the small Maf proteins, which are basic region and leucine zipper (bZIP)-type transcription factors. The HUGO Gene Nomenclature Committee-approved gene name of MAFG is “v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G”.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000197063 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000051510 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kataoka K, Igarashi K, Itoh K, Fujiwara KT, Noda M, Yamamoto M, Nishizawa M (Apr 1995). "Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor". Molecular and Cellular Biology. 15 (4): 2180–90. doi:10.1128/mcb.15.4.2180. PMC 230446. PMID 7891713.
^ "Entrez Gene: MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000197063 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000051510 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[Kataoka_1995-5] Kataoka K, Igarashi K, Itoh K, Fujiwara KT, Noda M, Yamamoto M, Nishizawa M (Apr 1995). "Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor". Molecular and Cellular Biology. 15 (4): 2180–90. doi:10.1128/mcb.15.4.2180. PMC 230446. PMID 7891713.

[entrez-6] "Entrez Gene: MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)".

MAFG information

and 12 Related for: MAFG information

MAFG

Small Maf

MAFK

List of human transcription factors

NFE2L2

BZIP Maf

Alliance Manchester Business School

NRF1

BZIP domain

Ngonidzashe Makusha

NFE2

NFE2L1