crystal structure of a luciferase domain from the dinoflagellate Lingulodinium polyedrum
Identifiers
Symbol
Luciferase_cat
Pfam
PF10285
InterPro
IPR018804
Available protein structures:
Pfam
structures / ECOD
PDB
RCSB PDB; PDBe; PDBj
PDBsum
structure summary
Dinoflagellate Luciferase/LBP N-terminal domain
Identifiers
Symbol
Luciferase_N
Pfam
PF05295
InterPro
IPR007959
Available protein structures:
Pfam
structures / ECOD
PDB
RCSB PDB; PDBe; PDBj
PDBsum
structure summary
Dinoflagellate Luciferase helical bundle domain
Identifiers
Symbol
Luciferase_3H
Pfam
PF10284
InterPro
IPR018475
Available protein structures:
Pfam
structures / ECOD
PDB
RCSB PDB; PDBe; PDBj
PDBsum
structure summary
Luciferase is a generic term for the class of oxidative enzymes that produce bioluminescence, and is usually distinguished from a photoprotein. The name was first used by Raphaël Dubois who invented the words luciferin and luciferase, for the substrate and enzyme, respectively.[1] Both words are derived from the Latin word lucifer, meaning "lightbearer", which in turn is derived from the Latin words for "light" (lux) and "to bring or carry" (ferre).[2]
Firefly luciferase
Structure of Photinus pyralis firefly luciferase.
Identifiers
Organism
Photinus pyralis
Symbol
Firefly luciferase
PDB
1LCI More structures
UniProt
P08659
Other data
EC number
1.13.12.7
Search for
Structures
Swiss-model
Domains
InterPro
Luciferases are widely used in biotechnology, for bioluminescence imaging[3] microscopy and as reporter genes, for many of the same applications as fluorescent proteins. However, unlike fluorescent proteins, luciferases do not require an external light source, but do require addition of luciferin, the consumable substrate.
^Lee J (28 February 2014). "A History of Bioluminescence". photobiology.info. Archived from the original on 29 March 2015.
^Lee J (September 2008). "Bioluminescence: the First 3000 Years (Review)". Journal of Siberian Federal University. Biology. 1 (3): 194–205. doi:10.17516/1997-1389-0264.
^Brennan CK, Ornelas MY, Yao ZW, Prescher JA (August 2021). "Multicomponent Bioluminescence Imaging with Naphthylamino Luciferins". ChemBioChem. 22 (16): 2650–2654. doi:10.1002/cbic.202100202. PMC 8496354. PMID 34139065.
Luciferase is a generic term for the class of oxidative enzymes that produce bioluminescence, and is usually distinguished from a photoprotein. The name...
Firefly luciferase is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles. The enzyme catalyses the oxidation...
generally called luciferin and luciferase, respectively. Because these are generic names, luciferins and luciferases are often distinguished by the species...
Dinoflagellate luciferase (EC 1.13.12.18, Gonyaulax luciferase) is a specific luciferase, an enzyme with systematic name dinoflagellate-luciferin:oxygen...
fungi present in decaying wood. The bluish-green glow is attributed to a luciferase, an oxidative enzyme, which emits light as it reacts with a luciferin...
express it to glow green under blue or ultraviolet light, the enzyme luciferase, which catalyzes a reaction with luciferin to produce light, and the red...
the enzyme luciferase and its regulatory gene, lux, have led to major advances in molecular biology, through use as a reporter gene. Luciferase was first...
detection using the firefly luciferase enzyme. A mixture of three enzymes (DNA polymerase, ATP sulfurylase and firefly luciferase) and a nucleotide (dNTP)...
light-emitting organs, usually on a female firefly's lower abdomen. The enzyme luciferase acts on luciferin, in the presence of magnesium ions, ATP, and oxygen...
their existing applications. Luciferase is a generic name for an enzyme that catalyzes a light-emitting reaction. Luciferases can be found in bacteria, algae...
Robinson falsely tweeted that the Moderna COVID-19 vaccine contained luciferase "so that you can be tracked." This echoed earlier false social media claims...
is highly efficient, by oxidation of luciferin catalyzed by enzymes (luciferases) in the presence of adenosine triphosphate (ATP) and oxygen, producing...
followed by 3 days of constant light (from 96h). Their genomes carry firefly luciferase reporter genes driven by the promoter sequences of clock genes. The signals...
both luciferases and photoproteins. Luciferins are a class of small-molecule substrates that react with oxygen in the presence of a luciferase (an enzyme)...
called 'Light Bearer', as the Latin word lucifer meant "light-bringing" Luciferase, a generic term for the class of oxidative enzymes used in bioluminescence...
luciferins whose usual light-producing reaction is catalyzed by the enzyme luciferase. The term photoprotein was first used to describe the unusual chemistry...
Robinson falsely tweeted that the Moderna COVID-19 vaccine contained luciferase "so that you can be tracked." This echoed earlier false social media claims...
infection. Another example of a visual marker useful in living cells is luciferase, an enzyme from the firefly which in the presence of luciferin, emits...
produced through its reaction with the naturally occurring firefly enzyme luciferase using a luminometer. The amount of light produced is directly proportional...
enzyme luciferase. This operon has a known gene sequence of luxCDAB(F)E, where luxA and luxB code for the protein subunits of the luciferase enzyme,...
specialized light organs adapted towards counter-illumination, but obtains the luciferase enzyme within these organs from bioluminescent ostracods, including Cypridina...
transport. Enzymes are also involved in more exotic functions, such as luciferase generating light in fireflies. Viruses can also contain enzymes for infecting...
include bioluminescent assays in which ATP is the limiting reagent for the luciferase reaction. Cytotoxicity can also be measured by the sulforhodamine B (SRB)...
emission from one of several organisms which bioluminesce, also known as luciferase enzymes. The three main sources are the North American firefly, the sea...
most effective buffer among the ten tested for ATP assays using firefly luciferase. Tricine has also been found to be an effective scavenger of hydroxyl...
N-terminal domain of Zophobas morio luciferase-like enzyme, inferences on the biological function and origin of oxygenase/luciferase activity". Photochemical &...
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